Eccrine porocarcinoma

MONDO:0006189

A carcinoma with eccrine differentiation arising from the sweat glands. It may arise de novo or as a malignant transformation of a pre-existing poroma. It usually grows in the legs, buttocks, feet, and trunk and usually presents as an ulcerative plaque. It is characterized by the presence of intraepidermal and dermal nests of malignant epithelial cells. It may recur after excision and metastasize to the lymph nodes and less frequently to distal anatomic sites.

Also known as: eccrine porocarcinoma, epidermotropic eccrine carcinoma, malignant eccrine poroma, porocarcinoma, eccrine porocarcinoma of skin, porocarcinoma/spiroadenocarcinoma

2768 clinical trials for this condition and its sub-types, 1 tagged with Eccrine porocarcinoma itself.

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Sub-types of Eccrine porocarcinoma

Vulvar eccrine porocarcinoma 0 trials

Including sub-types (2768) Tagged with Eccrine porocarcinoma (1)

Not yet finished but already full! 1

Cancer-Fighting virus teams up with immunotherapy to tackle rare skin tumors

Disease control Ongoing

This phase II trial is testing whether a combination of talimogene laherparepvec (a modified herpes virus that infects and kills cancer cells) and nivolumab (an immunotherapy drug) can shrink tumors in people with rare skin cancers or lymphomas that haven't responded to standard …

Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Aug 15, 2026 00:00 UTC

Eccrine porocarcinoma

Where it sits in the disease tree

Cancer-Fighting virus teams up with immunotherapy to tackle rare skin tumors