Early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome

Early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome is a genetic neurodegenerative disease characterized by normal early development followed by childhood onset optic atrophy with progressive vision loss and eventually blindness, followed by progressive neurological decline that typically includes cerebellar ataxia, nystagmus, dorsal column dysfunction (decreased vibration and position sense), spastic paraplegia and finally tetraparesis.

Also known as: NDGOA, SPG79, neurodegeneration with optic atrophy, childhood-onset, spastic paraplegia 79, autosomal recessive

2 clinical trials for this condition and its sub-types, 0 tagged with Early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome itself.