Disruptive behavior disorder

This study tests whether propranolol, a common blood pressure medication, can reduce aggression, self-injury, and severe disruptive behaviors in autistic adolescents and adults. Sixty participants will receive either propranolol or a placebo for 12 weeks, with the option to take …

This trial tests whether a brief, individually tailored parent training program—just three sessions with optional boosters—can reduce behavioral difficulties in children aged 2 to 12, compared to usual care. Parents of children referred to mental health centers are randomly assig…

This study tests whether a group-based parenting program called the Chicago Parent Program can improve executive function—skills like self-control and focus—in 4- and 5-year-olds from low-income families. Children and their parents will be randomly assigned to the program or a co…

This study tests whether parent coaching via video calls (Tele-PCIT) can help young children with disruptive behavior who are also at risk for trauma. About 50 families with children aged 2 to 6 will receive weekly one-hour coaching sessions over 12-16 weeks. The goal is to impro…

This study tests a stepped care approach for children aged 8-16 who struggle with anger, defiance, or aggression. All families start with a brief online parenting program. If more help is needed, they are randomly assigned to additional options, including virtual reality-assisted…

This trial tests a technology-based program called the Parenting Young Children Check-up (PYCC) for parents of children aged 2 to 5 with challenging behavior. Fifty parents from a Detroit pediatric clinic serving low-income families will be randomly assigned to either the program…

This trial tests a technology-based program called the Parenting Young Children Check-up (PYCC) for parents of children ages 2 to 5 with challenging behaviors. The program includes an initial check-up, text messages, and a website. Researchers will compare families who receive th…

This study tests a program called Invest in Play (iiP) for parents of children aged 6-12 with problem behaviors. About 180 families will be randomly assigned to the program or a control group. Parents will fill out surveys to see if the program reduces challenging behaviors and i…

This study tests whether an internet-based parent-child interaction therapy (I-PCIT) can help improve behavior in children aged 2-12 who have or had cancer. Parents of 300 children will be randomly assigned to start therapy right away or wait 5-6 months. The goal is to see if the…

This study tests whether middle-school students who have received disciplinary referrals can benefit from being trained as peer coaches. The Peer Coach Training (PCT) program is a strengths-based behavioral intervention that teaches skills for helping peers. Researchers will comp…

This study tests whether adding an AI app to standard behavioral parent training helps families with children aged 5-12 who have disruptive behaviors like irritability or ADHD. Forty parents will either attend 8 weekly online training sessions alone or with 24/7 access to an AI v…

This study tests two group-based parenting programs—HOT DOCS for children 0-5 and DOCS K-5 for kindergarten through 5th grade—designed to help caregivers manage disruptive behaviors and reduce parenting stress. Researchers will enroll 800 caregivers and professionals who speak En…

This study tests a training program for healthcare providers in Michigan to improve how they communicate with and care for Black and Hispanic pregnant individuals. The goal is to increase provider confidence and awareness of community resources, which may help reduce racial dispa…

This study looks at whether creating a personalized profile for children with disruptive behavior and their parents can help predict which treatment will work best. About 200 children and their parents will take part. The goal is to see if matching therapy to a child's specific e…

This study looks at how to help pediatric primary care offices better use a proven program called DOCC for children with behavior problems and ADHD. The program involves counseling and support for families. Researchers will compare different strategies to help clinic teams adopt …

This study watches 80 children (ages 8-15) with ADHD and emotional or behavioral problems to see how standard treatments like medication and group therapy affect their symptoms. Researchers compare treated kids to those on a waiting list, using questionnaires, computer tests, and…