Discoid lupus erythematosus
MONDO:0019558A chronic, autoimmune skin condition that manifests with a red, scaling rash, most often found on the face, ears, and scalp; these lesions often lead to permanent scarring and dyspigmentation. Patients may have lesions with or without other symptoms or antibodies suggestive of systemic lupus erythematosus (SLE).
Also known as: DLE
52 clinical trials for this condition and its sub-types, 17 tagged with Discoid lupus erythematosus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
Could a malaria pill tame discoid lupus?
Disease control Not yet recruitingThis study tests whether dihydroartemisinin, a drug used for malaria, can help treat discoid lupus erythematosus (DLE), a chronic skin condition causing red, scaly patches. Researchers will compare two doses of the drug to a standard lupus treatment (hydroxychloroquine) in 100 ad…
Phase 2 • Sponsor: Kunming Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
-
New pill aims to tame painful lupus skin flares
Disease control Not yet recruitingThis study is testing whether a pill called enpatoran can safely reduce active skin rashes in people with lupus. About 202 participants with moderate-to-severe lupus skin symptoms will take either enpatoran or a placebo pill for 24 weeks, while continuing their standard lupus med…
Phase 3 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC