Digestive system adenoma

MONDO:0006180

A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.

Also known as: digestive system adenoma, digestive tract adenoma, gastrointestinal adenoma

1569 clinical trials for this condition and its sub-types, 0 tagged with Digestive system adenoma itself.

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Where it sits in the disease tree

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Part of

↑ Digestive system neoplasm (7563) ↑ Adenoma (249)

Sub-types of Digestive system adenoma

Colorectal adenoma 96 trials · 120 incl. sub-types
4 sub-types
- Colon adenoma 17 trials · 32 incl. sub-types Sub-types →
- Colorectal sessile serrated adenoma/polyp 11 trials · 13 incl. sub-types Sub-types →
- Rectum adenoma 5 trials · 6 incl. sub-types Sub-types →
- Colorectal tubulovillous adenoma 1 trial Sub-types →
Adenoma of small intestine 1 trial · 4 incl. sub-types
4 sub-types
- Duodenal villous adenoma 2 trials
- Periampullary adenoma 2 trials
- Small intestinal tubular adenoma 0 trials
- Small intestinal tubulovillous adenoma 0 trials
Gastric adenoma 3 trials
1 sub-type
- Pyloric gland adenoma 0 trials
Warthin tumor 1 trial
Bile duct adenoma 0 trials
3 sub-types
- Bile duct cystadenoma 0 trials Sub-types →
- Extrahepatic bile duct adenoma 0 trials Sub-types →
- Intrahepatic bile duct adenoma 0 trials Sub-types →
Gallbladder adenoma 0 trials

Most studied deeper sub-types

Adenomatous colon polyp (12) Colon sessile serrated adenoma/polyp (11) Rectal traditional serrated adenoma (1) Appendix adenoma (0) Appendix villous adenoma (0) Bile duct mucinous cystic neoplasm with an associated invasive carcinoma (0) Cecum villous adenoma (0) Extrahepatic bile duct cystadenoma (0) Extrahepatic bile duct papillary adenoma (0) Intrahepatic bile duct cystadenoma (0) Rectal tubular adenoma (0) Rectal tubulovillous adenoma (0) Rectal villous adenoma (0) Villous adenoma of colon (0)

Including sub-types (1569) Tagged with Digestive system adenoma (0)

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