Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype
MONDO:0858939A high grade glioma that is characterized by the absence of histone H3, IDH1, and IDH2 mutations.
2987 clinical trials for this condition and its sub-types, 2 tagged with Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype itself.
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Nasal spray could deliver brain tumor treatment directly to Kids' tumors
Disease control Recruiting nowThis early-phase trial tests a nasal spray called NEO100 (a purified natural compound) in 12 children with certain aggressive brain tumors. The goal is to see if it's safe, find the best dose, and check if the drug reaches the tumor. Participants will receive increasing doses, an…
Phase 1 • Sponsor: Neonc Technologies, Inc. • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Radioactive drug targets brain tumors in early trial
Disease control Recruiting nowThis early-phase study tests a radioactive drug called 177Lu-PSMA-617 combined with standard chemotherapy (temozolomide) for people with aggressive IDH wild type gliomas. The goal is to see if the combination is safe and to get a first look at whether it helps control tumor growt…
Phase 1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC