Developmental and epileptic encephalopathy, 2
MONDO:0010396Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the CDKL5 gene.
Also known as: CDKL5 early infantile epileptic encephalopathy, DEE2, EIEE2, developmental and epileptic encephalopathy 2, X-linked dominant, developmental and epileptic encephalopathy, 2, early infantile epileptic encephalopathy caused by mutation in CDKL5, epileptic encephalopathy, early infantile, 2, epileptic encephalopathy, early infantile, type 2
26 clinical trials for this condition and its sub-types, 10 tagged with Developmental and epileptic encephalopathy, 2 itself.
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New drug trial aims to tame seizures in rare childhood disorder
Disease control Not yet recruitingThis study tests whether the drug ganaxolone can reduce seizures in children aged 6 months to 2 years with CDKL5 deficiency disorder, a rare genetic condition causing hard-to-control seizures. Twenty children will receive either ganaxolone or a placebo alongside their usual seizu…
Phase 3 • Sponsor: Immedica Pharma AB • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Hot baths tested as seizure treatment for rare childhood disorder
Symptom relief Not yet recruitingThis study tests whether taking a daily hot bath (40-42°C for 20 minutes) at home can reduce epileptic seizures in children with CDKL5 deficiency disorder. The trial will include 34 children aged 6 months to 14 years whose seizures are not controlled by medication. Researchers wi…
Sponsor: Xuanwu Hospital, Beijing • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC