Desmoplastic small round cell tumor
MONDO:0019373Desmoplastic small round cell tumor (DSRCT) is an aggressive soft tissue cancer that typically arises in serous lined surfaces of the abdominal or pelvic peritoneum, and spreads to the omentum, lymph nodes and hematogenously disseminates especially to the liver. Extraserous primary location has been reported in exceptional cases.
Also known as: DSRCT, Desmoplas. small round cell tumor, Desmoplas. small round cell tumour, Desmoplastic small round cell tumor, Desmoplastic small round cell tumour, Desmoplastic small round-cell neoplasm, Desmoplastic small round-cell tumor, Desmoplastic small round-cell tumour
2846 clinical trials for this condition and its sub-types, 26 tagged with Desmoplastic small round cell tumor itself.
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New immunotherapy targets genetic flaw in rare childhood cancers
Disease control Not yet recruitingThis study tests a new immunotherapy designed to help the immune system recognize and attack cancer cells in people with high-risk Ewing sarcoma or desmoplastic small round cell tumor (DSRCT). The treatment targets a specific genetic change found only in these cancer cells, aimin…
Phase 1 • Sponsor: Rabi Hanna • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Can a new drug tame ewing sarcoma when others fail?
Disease control Not yet recruitingThis phase 2 trial is testing an experimental drug called LX-101 to see if it can help control Ewing sarcoma and related tumors (DSRCT and SRCS) that have come back or stopped responding to standard chemotherapy. The study enrolls adolescents and young adults (age 10 and up) who …
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC