Decompression sickness
MONDO:0020797A condition occurring as a result of exposure to a rapid fall in ambient pressure. Gases, nitrogen in particular, come out of solution and form bubbles in body fluid and blood. These gas bubbles accumulate in joint spaces and the peripheral circulation impairing tissue oxygenation causing disorientation, severe pain, and potentially death.
Also known as: bends, decompression sickness, Bends, CAISSON DIS, Caisson Disease, Caisson Diseases, Caisson disease, Compressed air disease
5 clinical trials for this condition and its sub-types, 5 tagged with Decompression sickness itself.
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Could a simple prebreathe routine make spacewalks safer?
Knowledge-focused Not yet recruitingThis study tests whether different oxygen prebreathe routines and exercise levels can lower the risk of decompression sickness during simulated spacewalks. Healthy volunteers aged 30-60 breathe pure oxygen for an hour, then exercise in a low-pressure chamber to mimic space condit…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Divers with healed ear injuries may face hidden risks at depth
Knowledge-focused Not yet recruitingThis study looks at how nitrogen narcosis (a sleepy, dizzy feeling divers get at depth) affects hand-eye coordination, balance, and eye movements. Researchers will compare 20 healthy divers with 20 divers who previously had an inner ear decompression sickness. Participants perfor…
Sponsor: University of Plymouth • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC