Cutaneous undifferentiated pleomorphic sarcoma

MONDO:0002141

An undifferentiated pleomorphic sarcoma arising from the skin. It is characterized by the presence of spindle cells in a storiform pattern and histiocytes with abundant cytoplasm.

Also known as: cutaneous malignant fibrous histiocytoma, cutaneous unclassified pleomorphic sarcoma, cutaneous unclassified pleomorphic sarcoma (formerly cutaneous "MFH"), cutaneous unclassified pleomorphic sarcoma (formerly cutaneous "malignant fibrous histiocytoma"), cutaneous unclassified pleomorphic sarcoma (formerly cutaneous), cutaneous undifferentiated pleomorphic sarcoma, malignant cutaneous fibrous histiocytoma, malignant fibrous histiocytoma of skin

2845 clinical trials for this condition and its sub-types, 2 tagged with Cutaneous undifferentiated pleomorphic sarcoma itself.

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Where it sits in the disease tree

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Part of

↑ Undifferentiated pleomorphic sarcoma (48) ↑ Skin sarcoma (9)

Including sub-types (2845) Tagged with Cutaneous undifferentiated pleomorphic sarcoma (2)

Trials to join now! 1 Completed 1

New combo therapy shows promise for rare sarcomas

Disease control Completed

This study looked at adding the drug pazopanib to standard radiation or chemoradiation before surgery for patients with certain soft tissue sarcomas. The goal was to see if the combination is safe and helps shrink tumors more effectively. About 140 adults and children with newly …

Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Jun 27, 2026 14:00 UTC

Cutaneous undifferentiated pleomorphic sarcoma

Where it sits in the disease tree

New combo therapy shows promise for rare sarcomas