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Corticobasal syndrome

MONDO:0018696

Corticobasal syndrome (CBS) is a rare neurodegenerative disease characterized by multifaceted motor system dysfunctions and cognitive defects such as asymmetric rigidity, bradykinesia, limb apraxia, and visuospatial dysfunction.

32 clinical trials for this condition and its sub-types, 20 tagged with Corticobasal syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Inherited neurodegenerative disorder (808) ↑ Movement disorder (805) ↑ Hereditary dementia (322)

Including sub-types (32) Tagged with Corticobasal syndrome (20)

Trials to join now! 14 Not yet recruiting 2 Not yet finished but already full! 3 Completed 1

Could a common drug slow down this rare brain disease?

Disease control Completed

This phase 2 trial tests whether glycerol phenylbutyrate (GPB) can slow corticobasal syndrome (CBS), a rare and fast-progressing brain disease. 32 adults with CBS will receive either GPB or a placebo for 26 weeks. The main goal is to see if GPB lowers levels of a nerve damage mar…

Phase 2 • Sponsor: Technical University of Munich • Aim: Disease control

Last updated Sep 13, 2026 00:00 UTC