Connective tissue disorder
MONDO:0003900A disease involving the connective tissue.
Also known as: connective tissue disease, connective tissue disease or disorder, connective tissue diseases, connective tissue disorder, connective tissue disorders, disease of connective tissue, disease or disorder of connective tissue, disease, connective tissue
4637 clinical trials for this condition and its sub-types, 70 tagged with Connective tissue disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Connective tissue disorder
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Connective tissue neoplasm 1 trial · 2,404 incl. sub-types
13 sub-types
- Bone neoplasm 26 trials · 2,116 incl. sub-types Sub-types →
- Fibroblastic neoplasm 0 trials · 210 incl. sub-types Sub-types →
- Tumor of adipose tissue 1 trial · 98 incl. sub-types Sub-types →
- Chondrosarcoma 39 trials · 44 incl. sub-types Sub-types →
- Tenosynovial giant cell tumor 12 trials · 16 incl. sub-types Sub-types →
- Chondroma 4 trials Sub-types →
- Cholangiolocellular carcinoma 1 trial
- Solitary fibrous tumor/hemangiopericytoma 1 trial
- Angiomyxoma 0 trials
- Cartilage cancer 0 trials
- Dartoic leiomyoma 0 trials
- Lipofibromatosis-like neural tumor 0 trials
- Scirrhous adenocarcinoma 0 trials
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Rheumatic disorder 90 trials · 1,792 incl. sub-types
30 sub-types
- Rheumatoid arthritis 576 trials · 795 incl. sub-types Sub-types →
- Lupus erythematosus 39 trials · 548 incl. sub-types Sub-types →
- Scleroderma 47 trials · 305 incl. sub-types Sub-types →
- Autoinflammatory syndrome 21 trials · 207 incl. sub-types Sub-types →
- Juvenile idiopathic arthritis 107 trials · 115 incl. sub-types Sub-types →
- Dermatomyositis 81 trials · 100 incl. sub-types Sub-types →
- Polymyalgia rheumatica 30 trials
- Rheumatic fever 16 trials
- Mixed connective tissue disease 15 trials
- Reactive arthritis 6 trials
- Camptodactyly-arthropathy-coxa vara-pericarditis syndrome 4 trials
- Gorham-Stout disease 2 trials
- Sweet syndrome 2 trials
- Palindromic rheumatism 1 trial
- Rheumatic disease of mitral valve 1 trial
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- LAMA5-related multisystemic syndrome 0 trials
- Reye syndrome 0 trials
- Wissler syndrome 0 trials
- Acroosteolysis dominant type 0 trials
- Chondrocalcinosis 2 0 trials
- Fibroblastic rheumatism 0 trials
- Idiopathic juvenile osteoporosis 0 trials
- Intermittent hydrarthrosis 0 trials
- Interstitial granulomatous dermatitis with arthritis 0 trials
- Isolated sternocostoclavicular hyperostosis 0 trials
- Myalgia-eosinophilia syndrome associated with tryptophan 0 trials
- Progeria-associated arthropathy 0 trials
- Rheumatic pulmonary valve disease 0 trials
- Unexplained long-lasting fever/inflammatory syndrome 0 trials
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Hereditary disorder of connective tissue 0 trials · 1,311 incl. sub-types
88 sub-types
- Systemic lupus erythematosus 516 trials · 522 incl. sub-types Sub-types →
- Chronic myelogenous leukemia, BCR-ABL1 positive 211 trials · 253 incl. sub-types Sub-types →
- Uterine corpus leiomyoma 104 trials · 109 incl. sub-types Sub-types →
- Acquired polycythemia vera 90 trials
- Chondrosarcoma 39 trials · 44 incl. sub-types Sub-types →
- Type 2 collagenopathy 0 trials · 39 incl. sub-types Sub-types →
- CHILD syndrome 37 trials
- Desmoid tumor 36 trials Sub-types →
- Familial isolated pituitary adenoma 1 trial · 31 incl. sub-types Sub-types →
- Inherited acute myeloid leukemia 1 trial · 25 incl. sub-types Sub-types →
- Hereditary periodic fever syndrome 5 trials · 24 incl. sub-types Sub-types →
- Marfan and Marfan-related disorder 1 trial · 22 incl. sub-types Sub-types →
- VEXAS syndrome 18 trials
- Hypermobility spectrum disorder 16 trials
- Peyronie disease 12 trials
- Aicardi-Goutieres syndrome 9 trials Sub-types →
- Autosomal recessive inherited pseudoxanthoma elasticum 7 trials
- Ewing sarcoma of bone 5 trials
- TREX1-related type 1 interferonopathy 0 trials · 5 incl. sub-types Sub-types →
- Camptodactyly-arthropathy-coxa vara-pericarditis syndrome 4 trials
- Chronic recurrent multifocal osteomyelitis 3 trials · 4 incl. sub-types Sub-types →
- Blau syndrome 3 trials
- Ollier disease 3 trials
- Autoimmune interstitial lung disease-arthritis syndrome 3 trials Sub-types →
- Deficiency of adenosine deaminase 2 3 trials
- Hereditary multiple osteochondromas 3 trials Sub-types →
- Inherited torticollis 3 trials
- Maffucci syndrome 2 trials
- STING-associated vasculopathy with onset in infancy 2 trials
- Familial chilblain lupus 2 trials Sub-types →
- Proteosome-associated autoinflammatory syndrome 2 trials Sub-types →
- Sweet syndrome 2 trials
- ADAR-related type 1 interferonopathy 0 trials · 1 incl. sub-types Sub-types →
- Singleton-Merten dysplasia 1 trial Sub-types →
- Arterial tortuosity syndrome 1 trial
- Cherubism 1 trial Sub-types →
- Hyperparathyroidism 2 with jaw tumors 1 trial
- Infantile myofibromatosis 1 trial Sub-types →
- Neonatal severe primary hyperparathyroidism 1 trial
- Ossification of the posterior longitudinal ligament of the spine 1 trial
- EMILIN-1-related connective tissue disease 0 trials
- Ehlers-Danlos syndrome, kyphoscoliotic type 1 0 trials
- IFIH1-related type 1 interferonopathy 0 trials Sub-types →
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- LAMA5-related multisystemic syndrome 0 trials
- MASS syndrome 0 trials
- Pelger-Huet-like anomaly and episodic fever with abdominal pain 0 trials
- RNASEH2A-related type 1 interferonopathy 0 trials Sub-types →
- RNASEH2B-related type 1 interferonopathy 0 trials Sub-types →
- RNASEH2C-related type 1 interferonopathy 0 trials Sub-types →
- RNU7-1-related type 1 interferonopathy 0 trials Sub-types →
- SAMHD1-related type 1 interferonopathy 0 trials Sub-types →
- Sharpin-related autoinflammatory syndrome 0 trials
- Spondyloenchondrodysplasia with immune dysregulation 0 trials
- X-linked reticulate pigmentary disorder 0 trials
- Acroosteolysis dominant type 0 trials
- Aneurysmal bone cyst 0 trials
- Arterial tortuosity-bone fragility syndrome 0 trials
- Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation 0 trials
- Autoinflammatory disease, X-linked 0 trials
- Autoinflammatory disease, multisystem, with immune dysregulation, X-linked 0 trials Sub-types →
- Autoinflammatory disease, systemic, with vasculitis 0 trials
- Autoinflammatory syndrome with immunodeficiency 0 trials
- Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis 0 trials
- Autoinflammatory syndrome, familial, Behcet-like 0 trials Sub-types →
- Bone fragility with contractures, arterial rupture, and deafness 0 trials
- Brittle cornea syndrome 0 trials Sub-types →
- Chondrocalcinosis 2 0 trials
- Congenital progressive bone marrow failure-B-cell immunodeficiency-skeletal dysplasia syndrome 0 trials
- Diaphyseal medullary stenosis-bone malignancy syndrome 0 trials
- Encephalocraniocutaneous lipomatosis 0 trials
- Familial ossifying fibroma 0 trials
- Hyperparathyroidism 1 0 trials
- Hyperparathyroidism 3 0 trials
- Hyperparathyroidism 4 0 trials
- Idiopathic juvenile osteoporosis 0 trials
- Jugulotympanic paraganglioma 0 trials Sub-types →
- Juvenile hyaline fibromatosis 0 trials
- Linkeropathy 0 trials Sub-types →
- Multiple epiphyseal dysplasia due to collagen 9 anomaly 0 trials Sub-types →
- Multiple symmetric lipomatosis 0 trials Sub-types →
- Neonatal inflammatory skin and bowel disease 0 trials Sub-types →
- Progeroid and marfanoid aspect-lipodystrophy syndrome 0 trials
- Pseudo-TORCH syndrome 2 0 trials
- Psoriasis 14, pustular 0 trials
- Pyogenic arthritis-pyoderma gangrenosum-acne syndrome 0 trials
- Thrombocytopenia 6 0 trials
- Trichohepatoenteric syndrome 0 trials Sub-types →
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Disease of the tendon 126 trials · 192 incl. sub-types
3 sub-types
- Tendinitis 24 trials · 77 incl. sub-types Sub-types →
- Tendon sheath disorder 0 trials · 30 incl. sub-types Sub-types →
- Tendinosis 17 trials
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Benign connective and soft tissue neoplasm 0 trials · 101 incl. sub-types
5 sub-types
- Bone benign neoplasm 1 trial · 70 incl. sub-types Sub-types →
- Benign soft tissue neoplasm 0 trials · 16 incl. sub-types Sub-types →
- Benign lipomatous neoplasm 0 trials · 15 incl. sub-types Sub-types →
- Benign osteogenic neoplasm 0 trials Sub-types →
- Lipofibromatosis 0 trials
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Fasciitis 7 trials · 97 incl. sub-types
6 sub-types
- Plantar fasciitis 85 trials
- Necrotizing fasciitis 7 trials
- Eosinophilic fasciitis 1 trial
- Ischemic fasciitis 0 trials
- Nodular fasciitis 0 trials Sub-types →
- Proliferative fasciitis 0 trials
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Collagenopathy 3 trials · 42 incl. sub-types
3 sub-types
- Type 2 collagenopathy 0 trials · 39 incl. sub-types Sub-types →
- Disseminated eosinophilic collagen disease 0 trials
- Multiple epiphyseal dysplasia due to collagen 9 anomaly 0 trials Sub-types →
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Interstitial cystitis 39 trials
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Periostitis 0 trials · 16 incl. sub-types
2 sub-types
- Alveolar periostitis 16 trials
- Orbital periostitis 0 trials
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Synovitis 15 trials
1 sub-type
- Gonococcal synovitis 0 trials
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Overlapping connective tissue disease 2 trials · 15 incl. sub-types
2 sub-types
- Mixed connective tissue disease 15 trials
- MASS syndrome 0 trials
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Panniculitis 3 trials · 6 incl. sub-types
6 sub-types
- Lipodermatosclerosis 1 trial
- Nodular non-suppurative panniculitis 1 trial
- Panniculitis and localized lipodystrophy 1 trial
- Cytophagic histiocytic panniculitis 0 trials
- Erythema nodosum 0 trials
- Lupus erythematosus panniculitis 0 trials
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Enthesopathy 2 trials · 4 incl. sub-types
5 sub-types
- Enthesitis 2 trials
- Fibular collateral ligament bursitis 0 trials
- Olecranon bursitis 0 trials
- Pes anserinus tendinitis or bursitis 0 trials
- Tibial collateral ligament bursitis 0 trials
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Ochronosis disorder 1 trial
1 sub-type
- Exogenous ochronosis 0 trials
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Ainhum 0 trials
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Interstitial keratitis 0 trials
1 sub-type
- Diffuse interstitial keratitis 0 trials
Most studied deeper sub-types
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One-Time gene therapy aims to halt sanfilippo syndrome
Cure Not yet recruitingResearchers test a one-time gene therapy infusion in children and adults with Sanfilippo syndrome (MPS IIIB), a rare inherited disease that damages the brain and body. The therapy delivers a working copy of the NAGLU gene to help the body make an enzyme that is missing or faulty.…
Phase 1/2 • Sponsor: NeuroGT • Aim: Cure
Last updated Sep 16, 2026 00:00 UTC
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Could exercise be safe for a fragile blood vessel condition?
Disease control Not yet recruitingThis study explores whether a carefully designed, low-impact exercise program is safe and practical for people with vascular Ehlers-Danlos syndrome (vEDS), a rare condition that weakens blood vessels and organs. Researchers are working with patients and doctors to create a 12-wee…
Sponsor: Sheffield Hallam University • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Could a gum graft replace a membrane for better implant results?
Disease control Not yet recruitingThis study compares two ways to repair bone and gum defects during immediate dental implant placement. One group gets a standard collagen membrane, the other a connective tissue graft from the palate. Researchers want to see if the graft works just as well for bone healing while …
Sponsor: Universitat Internacional de Catalunya • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New study tests two techniques for better-looking dental implants
Disease control Not yet recruitingThis study compares two methods for placing a dental implant right after a tooth is pulled: the socket shield technique (leaving a small piece of tooth root) versus a connective tissue graft (using gum tissue from elsewhere). The goal is to see which approach better preserves the…
Sponsor: International Dental Contiuing Education • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New needling method could ease stubborn back pain
Symptom relief Not yet recruitingThis study looks at whether a special dry needling technique, called connective tissue dry needling, can help people with long-term low back pain caused by a specific spot near the hip bone. About 42 adults will either get the needling plus exercises, or just exercises, for two w…
Sponsor: University of Social Welfare and Rehabilitation Science • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Can a quick skin scan reveal hidden inflammation in arthritis?
Knowledge-focused Not yet recruitingThis study will measure harmful molecules called AGEs in 300 people with various rheumatic diseases (like rheumatoid arthritis and ankylosing spondylitis) and compare them to healthy volunteers. AGEs build up over time and can cause inflammation. Researchers will use a non-invasi…
Sponsor: Bursa City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Lupus patients wanted: new italian registry hopes to unlock better care
Knowledge-focused Not yet recruitingThe LUNET project is creating a registry of 1,500 Italian adults with systemic lupus erythematosus (SLE). By collecting real-world data from clinics across Italy, researchers hope to better understand the disease and improve how it is managed in daily practice. This is an observa…
Sponsor: Società Italiana di Allergologia, Asma e Immunologia Clinica • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:41 UTC