Congenital lobar emphysema
MONDO:0007536Congenital lobar emphysema (CLE) is a respiratory abnormality characterized by respiratory distress due to hyperinflation of one or more affected lobes of the lung.
Also known as: CLE, Emphysema, Congenital Lobar, congenital lobar hyperinflation, emphysema, congenital lobar, infantile lobar hyperinflation
15 clinical trials for this condition and its sub-types, 2 tagged with Congenital lobar emphysema itself.
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New antibody drug takes aim at autoimmune diseases
Disease control Recruiting nowThis early-stage study tests a new drug called SAR448501 (DR-0201) in 62 adults with lupus or rheumatoid arthritis. The drug is a bispecific antibody designed to target the immune system. The main goal is to check safety and find the right dose, not yet to prove it works. Partici…
Phase 1 • Sponsor: Sanofi • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New pill VENT-03 aims to calm lupus skin flares
Disease control Recruiting nowThis study tests an experimental tablet called VENT-03 for people with active cutaneous lupus erythematosus (CLE), a condition causing painful skin rashes. Twenty-four adults will take either VENT-03 or a placebo for 4 weeks, then everyone gets VENT-03 for 8 more weeks. Researche…
Phase 2 • Sponsor: Ventus Therapeutics U.S., Inc. • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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Boston study tests free AC and power subsidies to protect seniors from heat
Disease control Recruiting nowThis study is testing whether giving air conditioners and a $100 electricity subsidy to older adults in Boston neighborhoods can reduce heat stress, heat strain, and related health problems. One hundred participants aged 55-95 who don't have AC will be randomly assigned to receiv…
Sponsor: Harvard School of Public Health (HSPH) • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could racket sports boost lung rehab? small study tests feasibility
Symptom relief Recruiting nowThis study looks at whether Street Racket, a simple racket sport, can be added to standard pulmonary rehabilitation for people with chronic lung disease. Twelve participants will play Street Racket every two weeks during their rehab program. Researchers will measure how acceptabl…
Sponsor: Mona Lichtblau • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Partnerships with doctors may improve medical advice, study suggests
Knowledge-focused Recruiting nowThis study looks at how the relationship between doctors and patients affects the way medical decisions are made. Researchers will interview 300 patients and healthcare workers in Singapore to understand what makes a good partnership. The goal is to learn how these partnerships c…
Sponsor: Singapore General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Scientists probe sticky lung mucus to understand breathing disease
Knowledge-focused Recruiting nowThis study looks at the physical properties of lung mucus in people with obstructive pulmonary disease. Researchers will collect sputum samples before and after chest physiotherapy or exercise to see how these treatments change the mucus. The goal is to better understand the dise…
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC