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Congenital glaucoma
MONDO:0020366A developmental glaucoma that results from the abnormal development of the aqueous drainage structure, characterized by an elevated intra-ocular pressure, enlargement of globe (buphthalmos), corneal edema and optic nerve cupping, and presenting clinically with the characteristic triad of epiphora, photophobia and blepharospasm.
Also known as: Buphthalmus, buphthalmia, buphthalmos, hydrophthalmos, primary congenital glaucoma
15 clinical trials for this condition and its sub-types, 6 tagged with Congenital glaucoma itself.
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Sub-types of Congenital glaucoma
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Primary congenital glaucoma 2 trials · 4 incl. sub-types
3 sub-types
- CYP1B1-related glaucoma with or without anterior segment dysgenesis 0 trials · 2 incl. sub-types Sub-types →
- Glaucoma 3, primary congenital, C 0 trials
- Glaucoma 3, primary congenital, D 0 trials
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Glaucoma 3, primary congenital, E 0 trials
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Glaucoma 3, primary infantile, B 0 trials
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Glaucoma type 1C 0 trials
Most studied deeper sub-types
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New surgical twist may save sight in babies with rare glaucoma
Disease control CompletedThis study looks at a modified surgical technique for children with primary congenital glaucoma, a condition that causes high eye pressure and can lead to blindness if untreated. The surgery combines two procedures to create a better drainage channel for fluid inside the eye. Res…
Sponsor: Benha University • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Kids' glaucoma exams: standard anesthesia may improve accuracy
Knowledge-focused CompletedThis study looked at 120 children with glaucoma or suspected glaucoma who needed eye exams under anesthesia. The goal was to see if a standard anesthesia plan could produce consistent and reliable eye pressure measurements. Researchers measured how deep the anesthesia was and com…
Sponsor: Johannes Gutenberg University Mainz • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Early glaucoma detection in babies could save sight, study hints
Knowledge-focused CompletedThis study followed 250 children under 4 years old with congenital glaucoma in France. Researchers wanted to see if finding the disease earlier leads to better eyesight at age 4. They measured vision and eye pressure to understand how timing of diagnosis affects long-term outcome…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC