Congenital fibrosarcoma
MONDO:0004557A fibrosarcoma that occurs in infants. It shares identical morphologic features with adult fibrosarcoma but carries the t(12;15)(p13;q25) translocation that results in ETV6-NTRK3 gene fusion. It usually affects the superficial and deep soft tissues of the extremities. The prognosis is generally much more favorable than for adult fibrosarcoma, and it rarely metastasizes.
Also known as: congenital fibrosarcoma, infantile fibrosarcoma, infantile fibrosarcoma (congenital fibrosarcoma), infantile fibrosarcoma (morphologic abnormality), IFS
2980 clinical trials for this condition and its sub-types, 2 tagged with Congenital fibrosarcoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
New oral drug shows promise for kids with rare RET-Driven cancers
Disease control OngoingThis study tests an oral drug called selpercatinib (LOXO-292) in children with advanced solid or brain tumors that have a specific RET gene change. The trial has two parts: first finding a safe dose, then measuring how many children's tumors shrink. About 36 children whose cancer…
Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
-
New drug shows promise for rare childhood cancers
Disease control OngoingThis study tests a drug called larotrectinib in children and young adults (up to age 30) with certain cancers that have a specific genetic change called a TRK fusion. The goal is to see if the drug can shrink solid tumors or control leukemia that has returned. The drug works by b…
Phase 2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC