Congenital diaphragmatic hernia
MONDO:0005711A posterolateral defect of the diaphragm that allows passage of abdominal viscera into the thorax, leading to respiratory insufficiency and persistent pulmonary hypertension with high mortality.
Also known as: diaphragmatic hernia, CDH, congenital diaphragmatic hernia, agenesis of hemidiaphragm, congenital diaphragmatic defect, unilateral agenesis of diaphragm
46 clinical trials for this condition and its sub-types, 45 tagged with Congenital diaphragmatic hernia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Congenital diaphragmatic hernia
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Diaphragmatic hernia 1 1 trial
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Diaphragmatic hernia 2 0 trials
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Diaphragmatic hernia 3 0 trials
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Hernia, anterior diaphragmatic 0 trials
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Can a tiny balloon in the womb help babies breathe?
Disease control Not yet recruitingThis pilot trial tests a procedure called FETO for fetuses with severe congenital diaphragmatic hernia (CDH), a condition where the diaphragm has a hole and the lungs don't develop fully. In FETO, a balloon is temporarily placed in the fetal windpipe to encourage lung growth, the…
Sponsor: NYU Langone Health • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Can a simple gas help fragile newborns breathe easier?
Disease control Not yet recruitingThis study looks at whether inhaled nitric oxide can help newborns with a hole in their diaphragm (congenital diaphragmatic hernia) who also have high blood pressure in their lungs. About 40 babies will receive the gas, and doctors will check if their oxygen levels improve within…
Phase 4 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Balloon in the womb: new hope for babies with rare birth defect?
Disease control Not yet recruitingThis phase III trial tests a procedure called FETO for severe congenital diaphragmatic hernia (CDH), where the diaphragm is incomplete and organs move into the chest. Doctors place a temporary balloon in the baby's windpipe before birth to help the lungs grow. The study will comp…
Phase 3 • Sponsor: Oregon Health and Science University • Aim: Disease control
Last updated Jun 26, 2026 13:11 UTC
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New ultrasound technique could spot heart issues in newborns earlier
Knowledge-focused Not yet recruitingThis study tests a more sensitive ultrasound method called speckle tracking echocardiography (STE) to check heart function in newborns. Researchers will scan healthy babies and those with conditions like lung disease or oxygen deprivation to establish normal values and track chan…
Sponsor: Birmingham Women's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC