Complex regional pain syndrome type 2
MONDO:0020572Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia, not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.
Also known as: CRPS II, Complex regional pain syndrome II, causalgia
139 clinical trials for this condition and its sub-types, 18 tagged with Complex regional pain syndrome type 2 itself.
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Spinal stimulation without tingling: a new hope for failed back surgery pain?
Disease control OngoingThis study tests a type of spinal cord stimulation that uses low-level electrical pulses (below the sensation threshold) against the best available medical treatments for people with ongoing back and leg pain after back surgery. About 114 participants will be randomly assigned to…
Sponsor: Moens Maarten • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a tiny dose of naltrexone calm CRPS pain? new study aims to find out.
Symptom relief By invitation onlyThis study tests whether a very low dose of naltrexone, a drug usually used for addiction, can reduce pain and other symptoms in people with Complex Regional Pain Syndrome (CRPS). Forty adults with CRPS will receive either the drug or a placebo for six months. The main goal is to…
Phase 4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could a simple questionnaire replace In-Person exams for CRPS?
Knowledge-focused By invitation onlyThis study aims to validate a self-report questionnaire that people with Complex Regional Pain Syndrome (CRPS) can fill out at home. Researchers will compare the self-report results with in-person clinical exams to see if the questionnaire accurately measures symptom severity and…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC