Combined immunodeficiency due to DOCK8 deficiency

MONDO:0009478

Combined immunodeficiency due to dedicator of cytokinesis 8 protein (DOCK8) deficiency is a form of T and B cell immunodeficiency characterized by recurrent cutaneous viral infections, susceptibility to cancer and elevated serum levels of immunoglobulin E (IgE).

Also known as: Cid due to DOCK8 deficiency, DOCK8 immunodeficiency syndrome, combined immunodeficiency due to DOCK8 deficiency, combined immunodeficiency due to dedicator of cytokinesis 8 protein deficiency, dedicator of cytokinesis 8 deficiency, AR hyperimmunoglobulin E syndrome, AR-HIES, DOCK8 deficiency

46 clinical trials for this condition and its sub-types, 6 tagged with Combined immunodeficiency due to DOCK8 deficiency itself.

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↑ Hyper-IgE syndrome (26)

Including sub-types (46) Tagged with Combined immunodeficiency due to DOCK8 deficiency (6)

Trials to join now! 3 Not yet finished but already full! 2 Completed 1

New document helps young adults voice End-of-Life wishes

Knowledge-focused Completed

This study tested a document called Voicing My CHOiCES, designed to help young adults (ages 18-39) with serious illnesses like cancer or HIV discuss their care preferences. Participants filled out questionnaires about anxiety, social support, and communication, then reviewed the …

Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused

Last updated Sep 03, 2026 00:00 UTC

Combined immunodeficiency due to DOCK8 deficiency

Where it sits in the disease tree

New document helps young adults voice End-of-Life wishes