Collagenous gastritis

MONDO:0043355

A rare type of gastritis characterized by gastric subepithelial collagen deposition and inflammatory infiltrates in the lamina propria. The pathogenesis of this disorder is unclear although an association with autoimmune disorders has been reported. It affects both children and adults. Children present with iron deficiency anemia and have a nodular stomach on gastroscopy. adults present with chronic watery diarrhea and may have an associated collagenous colitis.

Also known as: collagenous gastritis

2 clinical trials for this condition and its sub-types, 1 tagged with Collagenous gastritis itself.

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Including sub-types (2) Tagged with Collagenous gastritis (1)

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Could a Crohn's drug tame a rare stomach disease?

Disease control Ongoing

This Phase 2 trial tests whether vedolizumab (Entyvio), a drug used for inflammatory bowel disease, can reduce symptoms of collagenous gastritis—a rare condition causing stomach pain, nausea, and bloating. Eleven participants receive the drug via IV and report their symptoms over…

Phase 2 • Sponsor: Massachusetts General Hospital • Aim: Disease control

Last updated Jun 27, 2026 14:00 UTC

Collagenous gastritis

Where it sits in the disease tree

Could a Crohn's drug tame a rare stomach disease?