Classic Hodgkin lymphoma
MONDO:0009348Classical Hodgkin lymphoma (CHL) is a B-cell lymphoma characterized histologically by the presence of large mononuclear Hodgkin cells and multinucleated Reed-Sternberg (HRS) cells.
Also known as: classic Hodgkin disease, classical Hodgkin lymphoma, classical Hodgkin's lymphoma, Chl, Hodgkin disease, Hodgkin lymphoma, susceptibility to, lymphoma, Hodgkin, classic
2041 clinical trials for this condition and its sub-types, 147 tagged with Classic Hodgkin lymphoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Classic Hodgkin lymphoma
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Engineered immune cells take on aggressive lymphomas in new trial
Disease control Not yet recruitingThis study tests a new treatment called CD70.CAR NK cells for people with diffuse large B-cell lymphoma or Hodgkin lymphoma that did not respond to or came back quickly after initial therapy. The treatment uses specially designed immune cells from a donor to find and attack cance…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New hope for hodgkin lymphoma: drug combo could replace chemo in relapsed patients
Disease control Not yet recruitingThis clinical trial is for people whose Hodgkin lymphoma has returned or not responded to first treatment. It has two parts: one for standard-risk patients testing a combination of targeted drugs (brentuximab vedotin and nivolumab) plus radiation, and another for high-risk patien…
Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New hope for kids with lymphoma: drug combo may replace harsh chemo
Disease control Not yet recruitingThis study tests a combination of two drugs, camrelizumab and ivarmacitinib, as a first treatment for children aged 6-18 with newly diagnosed classical Hodgkin lymphoma. The goal is to see if this approach can achieve a complete metabolic response (no signs of active cancer) whil…
Phase 1/2 • Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Immune cell therapy trial offers new hope for young hodgkin lymphoma patients
Disease control Not yet recruitingThis early-stage trial tests a new treatment for children, adolescents, and young adults with a certain type of Hodgkin lymphoma that has come back after initial therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack cancer…
Phase 1 • Sponsor: New York Medical College • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New CAR T-Cell combo trial targets tough hodgkin lymphoma in youth
Disease control Not yet recruitingThis trial tests whether giving CD30-targeting CAR T-cells after a strong chemotherapy and stem cell transplant is safe and feasible for children, teens, and young adults with poor-risk classical Hodgkin lymphoma. About 21 participants aged 6 to 29 will receive the treatment. The…
Phase 1/2 • Sponsor: New York Medical College • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Brain fog after lymphoma: study probes lasting cognitive effects of chemotherapy
Knowledge-focused Not yet recruitingThis study looks at thinking skills, memory, and quality of life in people who are 3 to 5 years past successful treatment for Hodgkin lymphoma or certain types of B-cell lymphoma. Participants take a series of tests and questionnaires once during a regular follow-up visit. The go…
Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC