CINCA syndrome
MONDO:0011776Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs.
Also known as: CINCA syndrome, CINCA/NOMID, IOMID syndrome, NOMID, NOMID syndrome, Neonatal-Onset Multisystem Inflammatory Disease, Prieur-Griscelli syndrome, chronic infantile neurological cutaneous and articular syndrome
15 clinical trials for this condition and its sub-types, 4 tagged with CINCA syndrome itself.
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New scan could reveal hidden organ damage without a biopsy
Diagnosis Recruiting nowThis study tests a radioactive tracer called 124I-AT-01 that binds to amyloid clumps in the body. Researchers want to see if PET/CT scans can detect amyloidosis in organs of people with CAPS who developed it from anakinra injections. Thirty adults will be scanned every 6 months f…
Phase 1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Diagnosis
Last updated Jun 27, 2026 12:35 UTC
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Massive study aims to unlock secrets of rare inflammatory diseases
Knowledge-focused Recruiting nowThis study is for people with certain autoinflammatory diseases (like NOMID, DIRA, CANDLE, SAVI, and others) and their healthy relatives. Researchers want to learn more about what causes these diseases and how they affect the body over time. Participants will have medical tests a…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Could your body clock affect rare inflammatory disease?
Knowledge-focused Recruiting nowThis study looks at whether people with CAPS (a rare genetic inflammatory condition) have disrupted circadian rhythms—the body's natural day-night cycle. Researchers will measure melatonin levels and track activity with a watch in 30 participants (patients and healthy household m…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC