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Choroideremia
MONDO:0010557Choroideremia (CHM) is an X-linked chorioretinal dystrophy characterized by progressive degeneration of the choroid, retinal pigment epithelium (RPE) and retina.
Also known as: CHM, Tapetochoroidal dystrophy, choroideremia, progressive choroidal atrophy, TCD, Tapetochoroidal dystrophy, progressive, choroidal sclerosis, progressive tapetochoroidal dystrophy
31 clinical trials for this condition and its sub-types, 6 tagged with Choroideremia itself.
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Sub-types of Choroideremia
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Choroideremia hypopituitarism 0 trials
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Total central choroidal atrophy 0 trials
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Gene Therapy's lasting effects on vision tracked in Long-Term study
Disease control CompletedThis study follows people with two inherited eye conditions—choroideremia and X-linked retinitis pigmentosa—who previously received gene therapy. Researchers monitor their safety and vision over several years to see if the treatment remains safe and helps preserve sight. Particip…
Phase 3 • Sponsor: NightstaRx Ltd, a Biogen Company • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Experimental eye injection aims to restore sight in rare blindness conditions
Disease control CompletedThis study tested an experimental drug called KIO-301, given as an injection into the eye, in 32 adults with retinitis pigmentosa or choroideremia—two inherited conditions that cause progressive vision loss. The main goal was to check safety and tolerability at increasing doses. …
Phase 1/2 • Sponsor: Kiora Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC