Childhood central nervous system primitive neuroectodermal neoplasm
MONDO:0002798A central nervous system embryonal tumor, not otherwise specified that occurs in childhood.
Also known as: Central nervous system embryonal tumor, NOS, central nervous system primitive neuroectodermal neoplasm of childhood, childhood CNS PNET, childhood CNS primitive neuroectodermal neoplasm, childhood CNS primitive neuroectodermal tumor, childhood CNS primitive neuroectodermal tumour, childhood central nervous system PNET, childhood central nervous system primitive neuroectodermal neoplasm
2938 clinical trials for this condition and its sub-types, 6 tagged with Childhood central nervous system primitive neuroectodermal neoplasm itself.
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Sub-types of Childhood central nervous system primitive neuroectodermal neoplasm
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Pediatric cerebral ependymoblastoma 0 trials
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Immune cells engineered to hunt brain tumors in kids
Disease control Recruiting nowThis early-phase trial tests a new treatment for children and young adults with medulloblastoma or similar brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack tumor cells, deliv…
Phase 1 • Sponsor: Stanford University • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Killer virus turned against childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether a specially engineered herpes virus (G207) is safe to inject directly into the brain tumors of children whose cancer has returned. Up to 24 children aged 3 to 21 will receive the virus, and some will also get a small dose of radiation to help …
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New hope for toddlers with aggressive brain cancer: experimental spinal-fluid chemo
Disease control Recruiting nowThis early-phase study tests whether adding chemotherapy directly into the spinal fluid (intrathecal topotecan) followed by maintenance pills is feasible for children under 6 with high-risk embryonal brain tumors. About 15 children will receive this treatment after standard high-…
Early phase 1 • Sponsor: C17 Council • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Tailor-Made T-Cells take on childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether personalized immune cells (T-cells) can safely treat young children with aggressive brain tumors. The T-cells are designed to attack unique markers found on each child's tumor. Up to 12 children under 5 with embryonal brain tumors or recurrent…
Phase 1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for kids with tough brain tumors: gene therapy meets immunotherapy and radiation
Disease control Recruiting nowThis early-phase trial is testing a combination of three treatments for children whose brain tumors have come back or not responded to standard care. The experimental drug SGT-53 delivers a normal TP53 gene to tumor cells, and is given alongside the immunotherapy Nivolumab and ra…
Early phase 1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC