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Chagas disease

MONDO:0001444

A parasitic infection caused by Trypanosoma cruzi. It is transmitted by insect bites. It is characterized by an acute and chronic phase; in the acute phase patients may have fever, malaise, and swelling at the site of the insect bite. In the chronic phase patients develop hepatosplenomegaly, lymphadenopathy, cardiomyopathy and arrhythmias.

Also known as: Chagas disease, Chagas' disease, Trypanosoma cruzi caused disease or disorder, Trypanosoma cruzi disease or disorder, Trypanosoma cruzi infectious disease, infection by trypanosoma cruzi, Chagas-mazza disease, infection caused by trypanosoma cruzi

13 clinical trials for this condition and its sub-types, 12 tagged with Chagas disease itself.

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Where it sits in the disease tree

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Part of

↑ Vector-borne disease (448) ↑ Trypanosomiasis (15)

Including sub-types (13) Tagged with Chagas disease (12)

Trials to join now! 2 Not yet recruiting 2 Not yet finished but already full! 1 Completed 7

Chagas drug shows promise for kids in landmark trial

Disease control Ongoing

This study tests whether the drug benznidazole can cure chronic Chagas disease in children aged 2 to 18. All 178 participants receive the drug, and their results are compared to a historical placebo group. The main goal is to see if the infection clears based on blood tests over …

Phase 3 • Sponsor: Insud Pharma • Aim: Disease control

Last updated Jun 27, 2026 12:23 UTC

Chagas disease

Where it sits in the disease tree

Chagas drug shows promise for kids in landmark trial