Cerebral sinovenous thrombosis
MONDO:0017993A rare but serious cerebrovascular disorder involving thrombosis of the cerebral venous system. It affects children from the newborn period through childhood and adolescence. In childhood CSVT, acute infections of the head and neck such as mastoiditis are most common, followed by chronic underlying diseases such as nephrotic syndrome, cancer, and inflammatory bowel disease. Signs and symptoms are also age related. Seizures and altered mental status are the commonest manifestations in newborns. Headache, vomiting, and lethargy, sometimes with 6th nerve palsy, are the most common symptoms in children and adolescents.
Also known as: CSVT
26 clinical trials for this condition and its sub-types, 16 tagged with Cerebral sinovenous thrombosis itself.
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Can an Anti-Inflammatory drug improve recovery from a rare stroke type?
Disease control Recruiting nowThis trial tests whether adding tocilizumab, an anti-inflammatory drug, to standard blood thinners improves recovery in people with acute cerebral venous thrombosis, a type of stroke caused by a blood clot in the brain's veins. Researchers will give 80 adults either a single infu…
Sponsor: Capital Medical University • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Snake venom enzyme could boost stroke recovery in rare brain clot study
Disease control Recruiting nowThis study tests whether adding batroxobin, a snake venom enzyme that dissolves clots, to standard blood thinners helps people with acute cerebral venous thrombosis (a rare stroke caused by a clot in a brain vein). Seventy-two adults will be randomly assigned to receive either st…
Phase 4 • Sponsor: Xuanwu Hospital, Beijing • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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One-Dose antibiotic could slash ventilator pneumonia deaths in brain injury patients
Prevention Recruiting nowThis study tests whether giving a single dose of a common antibiotic soon after a breathing tube is placed can prevent lung infections and improve survival in ICU patients with severe brain injuries. Researchers will enroll 3,300 adults on ventilators due to stroke, trauma, or la…
Phase 3 • Sponsor: The George Institute • Aim: Prevention
Last updated Aug 30, 2026 00:00 UTC
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Decades of data: can a citywide registry unlock the secrets of stroke and dementia?
Knowledge-focused Recruiting nowThis study is a long-running registry that collects detailed health information from all stroke and dementia patients in Erlangen, Germany. It aims to understand how these diseases develop and affect people over time, regardless of age or severity. Participants are followed for l…
Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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3000 patients join study to unravel brain clot mystery
Knowledge-focused Recruiting nowThis study is following 3000 people in China who have cerebral venous thrombosis, a rare type of blood clot in the brain. Researchers will collect blood and spinal fluid samples to learn more about the disease and find markers that could help with diagnosis. The goal is to better…
Sponsor: Capital Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Brain vein study tests new MRI to see lymph nodes
Knowledge-focused Recruiting nowThis pilot study aims to see if a special MRI sequence can detect lymphatic damage in people with brain vein narrowing or clots. About 100 adults will get an extra MRI scan during their regular care. No new treatment is tested; the goal is to learn if this MRI method can spot lym…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC