Central precocious puberty
MONDO:0019165Central precocious puberty (CPP), also referred to as gonadotropin dependent precocious puberty, is an endocrine-related developmental disease characterized by the onset of pubertal changes, with development of secondary sexual characteristics and accelerated growth and bone maturation, before the normal age of puberty (8 years in girls and 9 years in boys).
Also known as: gonadotropin-dependant precocious puberty, gonadotropin-dependent precocious puberty, precocious puberty, central
10 clinical trials for this condition and its sub-types, 9 tagged with Central precocious puberty itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Central precocious puberty
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Central precocious puberty 1 0 trials
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Central precocious puberty in male 0 trials
2 sub-types
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Precocious puberty, central, 2 0 trials
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Secondary central precocious puberty 0 trials
Most studied deeper sub-types
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Monthly shot may pause early puberty in children
Disease control Recruiting nowThis study tests whether a monthly injection of leuprorelin, a drug that blocks puberty hormones, can safely slow or stop early puberty in children diagnosed with central precocious puberty. About 43 children—girls under 9 and boys under 10—will receive the injection every 4 week…
Phase 4 • Sponsor: LG Chem • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Early puberty and brain disorders: a new look at the link
Knowledge-focused Recruiting nowThis study looks at 300 children with central precocious puberty (early puberty) to see how many also have a neurodevelopmental syndrome or condition. Researchers will compare the diagnosis and development of children with early puberty alone versus those with an associated brain…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC