Central pontine myelinolysis
MONDO:0006692A central nervous system disorder caused by demyelination within the central basis pontis of the brain. It is characterized by spastic quadriplegia, pseudobulbar palsy and encephalopathy. It is observed in patients with severe hyponatremia, particularly when the hyponatremia is corrected too rapidly.
3 clinical trials for this condition and its sub-types, 2 tagged with Central pontine myelinolysis itself.
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Massive review seeks to uncover hidden dangers of severe low sodium
Knowledge-focused By invitation onlyThis study looks back at the medical records of 800 people who were hospitalized with dangerously low sodium levels (≤110 mmol/L). Researchers want to learn how often serious brain complications like swelling or nerve damage occur, and how treatment affects these risks. No new tr…
Sponsor: Rochester General Hospital • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Massive study aims to uncover hidden dangers of low sodium
Knowledge-focused OngoingThis study looks back at 10,000 hospital patients to learn more about low sodium levels (hyponatremia). Researchers want to know how common it is, how fast doctors correct it, and whether that affects patient outcomes like brain damage or death. No new drug or treatment is being …
Sponsor: University of Turku • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC