Catecholaminergic polymorphic ventricular tachycardia 1

MONDO:0011484

Polymorphic ventricular tachycardia induced by adrenergic stress. It is inherited in an autosomal dominant pattern and is caused by mutations in the ryanodine receptor 2 (RYR2) gene.

Also known as: ARVC2, ARVD2, RYR2 familial isolated arrhythmogenic right ventricular dysplasia, arrhythmogenic right ventricular cardiomyopathy 2, arrhythmogenic right ventricular dysplasia 2, arrhythmogenic right ventricular dysplasia type 2, arrhythmogenic right ventricular dysplasia, familial, type 2, catecholaminergic polymorphic ventricular tachycardia 1

43 clinical trials for this condition and its sub-types, 2 tagged with Catecholaminergic polymorphic ventricular tachycardia 1 itself.

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↑ Catecholaminergic polymorphic ventricular tachycardia (10) ↑ Familial isolated arrhythmogenic right ventricular dysplasia (10)

Including sub-types (43) Tagged with Catecholaminergic polymorphic ventricular tachycardia 1 (2)

Completed 1 Terminated 1

Heart drug study halted early: what we know

Disease control Stopped early

This study tested an experimental drug called CRD-4730 in people with a rare inherited heart rhythm disorder (CPVT) that can cause dangerous fast heartbeats. Seven adults received two different doses of the drug and a placebo to check safety and how the body processes it. The stu…

Phase 2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control

Last updated Jun 27, 2026 12:38 UTC

Catecholaminergic polymorphic ventricular tachycardia 1

Where it sits in the disease tree

Heart drug study halted early: what we know