Carcinoma of the ampulla of vater
MONDO:0017590A carcinoma arising from the ampulla of Vater. The vast majority of cases are adenocarcinomas. Signs and symptoms include jaundice, abdominal pain, anorexia, nausea, vomiting, and weight loss.
Also known as: Ampulloma, ampulla of Vater cancer, ampulla of Vater carcinoma, ampullary cancer, ampullary carcinoma, carcinoma of ampulla of vater, carcinoma of hepatopancreatic ampulla, hepatopancreatic ampulla carcinoma
3025 clinical trials for this condition and its sub-types, 29 tagged with Carcinoma of the ampulla of vater itself.
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Sub-types of Carcinoma of the ampulla of vater
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Ampulla of vater adenocarcinoma 11 trials · 42 incl. sub-types
4 sub-types
- Periampullary adenocarcinoma 33 trials
- Ampulla of vater clear cell adenocarcinoma 0 trials
- Ampulla of vater mucinous adenocarcinoma 0 trials
- Ampullary signet ring cell adenocarcinoma 0 trials
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1 sub-type
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Can a targeted pill shrink hard-to-treat bile duct cancers?
Disease control Not yet recruitingThis phase 2 trial tests whether daraxonrasib, an oral drug that targets cancers with a KRAS mutation, can shrink tumors in people with advanced biliary tract cancer that has progressed after first-line treatment. Participants take the drug once daily in 28-day cycles. The main g…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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Smartwatch-Guided prehab aims to boost pancreatic surgery recovery
Disease control Not yet recruitingThis trial tests whether a wearable device and a personalized prehabilitation program can help adults recover better after surgery for pancreatic cancer or related conditions. Participants will wear a monitor to track vital signs and activity, and follow a program of exercise, nu…
Sponsor: Manchester University NHS Foundation Trust • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New drainage technique may reduce pancreatitis risk after tumor surgery
Disease control Not yet recruitingThis study tests whether using a gentle suction tube (negative-pressure drainage) is better than placing a small plastic tube (stent) in the pancreas to prevent pancreatitis after removing tumors from the duodenum. About 132 adults with early-stage tumors will be randomly assigne…
Sponsor: Cui Xiaobing • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Lab test may guide smarter chemo for bile duct cancer patients
Disease control Not yet recruitingThis study tests whether a lab test (3D-PTA) that checks which chemotherapy drugs work best on a patient's tumor can improve outcomes after bile duct cancer surgery. About 98 adults with stage II/III bile duct cancer will be randomly assigned to receive either standard capecitabi…
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC