Butyrylcholinesterase deficiency

MONDO:0015270

Butyrylcholinesterase (BChE) deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency.

Also known as: apnea, postanesthetic, susceptibility to, due to BCHE deficiency, butyrylcholinesterase deficiency, Acholinesterasemia, BCHED, Suxamethonium sensitivity, apnea, postanesthetic, butyrylcholinesterase deficiency, fluoride-resistant, Japanese type, cholinesterase 2 deficiency

3 clinical trials for this condition and its sub-types, 3 tagged with Butyrylcholinesterase deficiency itself.

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Where it sits in the disease tree

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Part of

↑ Metabolic disease involving other neurotransmitter deficiency (3)

Including sub-types (3) Tagged with Butyrylcholinesterase deficiency (3)

Trials to join now! 1 Not yet recruiting 1 Not yet finished but already full! 1

Baby drug dosing study aims to prevent post-surgery breathing problems

Knowledge-focused Not yet recruiting

This study will find the correct dose of sugammadex, a drug that reverses muscle relaxants, for infants under 2 years old. About 99 babies having non-emergency surgery will receive small, increasing doses until their muscle function returns. The goal is to ensure safe and complet…

Phase 4 • Sponsor: University Hospital, Caen • Aim: Knowledge-focused

Last updated Jun 27, 2026 11:02 UTC

Butyrylcholinesterase deficiency

Where it sits in the disease tree

Baby drug dosing study aims to prevent post-surgery breathing problems