Brain glioblastoma
MONDO:0002501A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.
Also known as: brain glioblastoma, brain glioblastoma (disease), brain glioblastoma multiforme, brain glioblastoma multiforme (disease), glioblastoma multiforme of brain, glioblastoma multiforme of the brain, grade IV astrocytic tumour of brain, grade IV brain astrocytic tumour
2976 clinical trials for this condition and its sub-types, 24 tagged with Brain glioblastoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Brain glioblastoma
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Gliosarcoma 65 trials
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Giant cell glioblastoma 7 trials
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Brain stem glioblastoma 1 trial
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Immune booster vaccine shows promise against deadly brain cancer
Disease control OngoingThis study tests whether adding a personalized dendritic cell vaccine to standard chemotherapy can help people with newly diagnosed glioblastoma live longer. Twenty patients who had surgery and chemoradiation will receive the vaccine alongside temozolomide. The goal is to see if …
Phase 1/2 • Sponsor: University Hospital, Antwerp • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Belly tissue used to bypass brain barrier in cancer fight
Disease control PausedThis early-stage trial tests a new surgical approach for recurrent glioblastoma, an aggressive brain cancer. After standard tumor removal, surgeons place a piece of abdominal tissue (omentum) into the brain cavity to bypass the blood-brain barrier. The study involves 10 adults an…
Phase 1 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could a pill reach and fight aggressive brain tumors? early trial hints at possibility
Disease control OngoingThis early-phase trial tests the drug niraparib (Zejula) in people with two types of brain cancer: newly diagnosed glioblastoma and recurrent glioma with specific genetic changes (IDH mutation and ATRX loss). The study first checks if the drug reaches the tumor tissue, then gives…
Early phase 1 • Sponsor: Nader Sanai • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Lifting weights, lifting hope: exercise trial targets brain cancer decline
Symptom relief By invitation onlyThis study explores whether a supervised, circuit-based resistance training program can help glioblastoma patients maintain muscle mass and perform daily tasks more easily. Researchers will enroll 24 adults with glioblastoma who are currently on treatment. Participants will exerc…
Sponsor: Nova Scotia Health Authority • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC