Brain glioblastoma
MONDO:0002501A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.
Also known as: brain glioblastoma, brain glioblastoma (disease), brain glioblastoma multiforme, brain glioblastoma multiforme (disease), glioblastoma multiforme of brain, glioblastoma multiforme of the brain, grade IV astrocytic tumour of brain, grade IV brain astrocytic tumour
2976 clinical trials for this condition and its sub-types, 24 tagged with Brain glioblastoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Brain glioblastoma
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Gliosarcoma 65 trials
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Giant cell glioblastoma 7 trials
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Brain stem glioblastoma 1 trial
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Can a modified herpes virus outsmart brain cancer?
Disease control CompletedThis phase 1 trial tests a genetically engineered virus called C134, made from a herpes simplex virus, in people with recurrent malignant glioma, a type of brain cancer. The virus is injected directly into the tumor, where it aims to infect and kill cancer cells while also trigge…
Phase 1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Brain cancer vaccine shows promise in early trial
Disease control CompletedThis early-phase study tested a personalized vaccine made from a patient's own immune cells (dendritic cells) combined with standard chemotherapy (temozolomide) for adults with newly diagnosed glioblastoma, an aggressive brain cancer. Eleven patients who had most of their tumor r…
Phase 1 • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC