Blood coagulation disease
MONDO:0001531A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.
Also known as: blood coagulation disorder, coagulation defect, coagulation disorder, coagulation disorder, blood, coagulation disorders, blood, coagulopathy, disorder, blood coagulation, disorders, blood coagulation
541 clinical trials for this condition and its sub-types, 54 tagged with Blood coagulation disease itself.
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Sub-types of Blood coagulation disease
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Inherited blood coagulation disorder 8 trials · 323 incl. sub-types
39 sub-types
- Hemophilia A 180 trials Sub-types →
- Hemophilia B 84 trials · 91 incl. sub-types Sub-types →
- Hereditary von Willebrand disease 18 trials · 29 incl. sub-types Sub-types →
- Inherited thrombophilia 0 trials · 28 incl. sub-types Sub-types →
- Hereditary hemolytic uremic syndrome 0 trials · 19 incl. sub-types Sub-types →
- Wiskott-Aldrich syndrome 10 trials
- Glanzmann thrombasthenia 8 trials Sub-types →
- Platelet-type bleeding disorder 10 8 trials
- Congenital thrombotic thrombocytopenic purpura 5 trials
- Hereditary thrombocytopenia and hematologic cancer predisposition syndrome 1 trial · 5 incl. sub-types Sub-types →
- Hermansky-Pudlak syndrome 4 trials Sub-types →
- Congenital vitamin K-dependent coagulation factors deficiency 0 trials · 4 incl. sub-types Sub-types →
- Congenital factor XII deficiency 1 trial
- Congenital plasminogen activator inhibitor type 1 deficiency 1 trial
- Hypoplasminogenemia 1 trial
- Ehlers-Danlos syndrome, fibronectinemic type 0 trials
- Scott syndrome 0 trials
- Tatsumi factor deficiency 0 trials
- Alpha-2-plasmin inhibitor deficiency 0 trials
- Congenital factor V deficiency 0 trials
- Congenital factor XI deficiency 0 trials
- Congenital high-molecular-weight kininogen deficiency 0 trials
- Cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder 0 trials
- Dysplasminogenemia 0 trials
- Factor 5 and Factor VIII, combined deficiency of, 2 0 trials
- Factor V and factor VIII, combined deficiency of, type 1 0 trials
- Factor VII and Factor VIII, combined deficiency of 0 trials
- Factor XIII, A subunit, deficiency of 0 trials
- Factor XIII, b subunit, deficiency of 0 trials
- Familial thrombomodulin anomalies 0 trials
- Hereditary thrombocytosis with transverse limb defect 0 trials
- Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency 0 trials
- Inherited prekallikrein deficiency 0 trials
- Plasminogen deficiency, type II 0 trials
- Platelet-type bleeding disorder 12 0 trials
- Platelet-type bleeding disorder 14 0 trials
- Platelet-type bleeding disorder 16 0 trials
- Platelet-type bleeding disorder 18 0 trials
- Platelet-type bleeding disorder 8 0 trials
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Coagulation protein disease 13 trials · 274 incl. sub-types
28 sub-types
- Hemophilia 55 trials · 216 incl. sub-types Sub-types →
- Von Willebrand disease (hereditary or acquired) 39 trials · 46 incl. sub-types Sub-types →
- Acquired coagulation factor deficiency 4 trials · 16 incl. sub-types Sub-types →
- Congenital fibrinogen deficiency 2 trials · 6 incl. sub-types Sub-types →
- Factor VII deficiency 6 trials Sub-types →
- Thrombophilia due to activated protein C resistance 5 trials
- Congenital vitamin K-dependent coagulation factors deficiency 0 trials · 4 incl. sub-types Sub-types →
- Factor X deficiency 2 trials Sub-types →
- Congenital factor XII deficiency 1 trial
- Congenital plasminogen activator inhibitor type 1 deficiency 1 trial
- Hypoplasminogenemia 1 trial
- East Texas bleeding disorder 0 trials
- Tatsumi factor deficiency 0 trials
- Alpha-2-plasmin inhibitor deficiency 0 trials
- Combined deficiency of factor V and factor VIII 0 trials Sub-types →
- Combined deficiency of factor VII and factor X 0 trials
- Congenital high-molecular-weight kininogen deficiency 0 trials
- Dysplasminogenemia 0 trials
- Factor V amsterdam bleeding disorder 0 trials
- Factor V atlanta bleeding disorder 0 trials
- Factor V deficiency 0 trials Sub-types →
- Factor V short isoforms-related bleeding disorder 0 trials
- Factor XIII deficiency 0 trials Sub-types →
- Hemorrhagic disease due to alpha-1-antitrypsin Pittsburgh mutation 0 trials
- Inherited prekallikrein deficiency 0 trials
- Multiple sclerosis-ichthyosis-factor VIII deficiency syndrome 0 trials
- Plasminogen deficiency, type II 0 trials
- Thrombomodulin-related bleeding disorder 0 trials
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Thrombotic microangiopathy 26 trials · 151 incl. sub-types
2 sub-types
- Thrombocytopenic purpura 8 trials · 116 incl. sub-types Sub-types →
- Atypical hemolytic-uremic syndrome 19 trials Sub-types →
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Thrombophilia 12 trials · 75 incl. sub-types
4 sub-types
- Inherited thrombophilia 0 trials · 28 incl. sub-types Sub-types →
- Thrombotic thrombocytopenic purpura 15 trials · 20 incl. sub-types Sub-types →
- Disseminated intravascular coagulation 15 trials Sub-types →
- Protein S deficiency 3 trials Sub-types →
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Hemolytic-uremic syndrome 7 trials · 24 incl. sub-types
2 sub-types
- Hereditary hemolytic uremic syndrome 0 trials · 19 incl. sub-types Sub-types →
- Infection-related hemolytic uremic syndrome 0 trials · 2 incl. sub-types Sub-types →
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Hemorrhagic disease of newborn 1 trial
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Marantic endocarditis 0 trials
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Prekallikrein deficiency 0 trials
1 sub-type
- Inherited prekallikrein deficiency 0 trials
Most studied deeper sub-types
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Can a japanese ARDS drug fix deadly clots in septic shock?
Disease control Not yet recruitingThis study tests whether sivelestat, a drug used in Japan for lung injury, can help restore the body's ability to break down harmful blood clots in people with septic shock. About 120 adults with septic shock and early blood clotting problems will receive either sivelestat or a p…
Phase 2 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Ginger vs. heavy periods: a natural approach for women with bleeding disorders
Symptom relief Not yet recruitingThis study tests whether taking ginger powder for the first three days of each period can reduce heavy menstrual bleeding in women with coagulation disorders (bleeding problems). 74 women will be randomly assigned to receive either ginger or a placebo for six cycles. The goal is …
Early phase 1 • Sponsor: University of Valladolid • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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New study to define healthy blood clotting ranges for kids
Knowledge-focused Not yet recruitingThis study will measure normal blood clotting values in 240 children under 18 who are having surgery or a procedure with anesthesia. The goal is to establish reference ranges for the Quantra system, a device that checks how well blood clots. This information will help doctors bet…
Sponsor: HemoSonics LLC • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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New blood test may predict bleeding risk after heart surgery
Knowledge-focused Not yet recruitingThis study looks at whether a new test called T-TAS can help predict bleeding after heart surgery. Researchers will take blood samples from 30 adults before, right after, and 24 hours after surgery. They will compare T-TAS results with standard tests and track how much bleeding a…
Sponsor: Hospital de la Santa creu i Sant Pau - Barcelona • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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AI takes on blood clotting tests: could it outsmart the experts?
Knowledge-focused Not yet recruitingThis study will compare how well an artificial intelligence (AI) system and human experts interpret ROTEM tests, which measure blood clotting in patients undergoing surgery or in critical care. Researchers will enroll 400 adults and assess agreement on whether a clotting problem …
Sponsor: Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC