Barrett adenocarcinoma
MONDO:0004405An adenocarcinoma arising from Barrett metaplastic epithelium in the esophagus. There is evidence supporting the idea that the Barrett adenocarcinomas develop through a stepwise progression through intestinal metaplastic epithelium to epithelial dysplasia to malignancy. Adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. In terms of grading, they are well or moderately differentiated adenocarcinomas. -- 2002
Also known as: Barrett adenocarcinoma, Barrett's adenocarcinoma, adenocarcinoma arising in Barrett's mucosa
2883 clinical trials for this condition and its sub-types, 6 tagged with Barrett adenocarcinoma itself.
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New cutting tool may outperform heat therapy for Barrett's esophagus
Disease control Recruiting nowThis study tests a new device called EndoRotor, which mechanically removes the damaged lining of the esophagus, against the standard heat-based radiofrequency treatment for people with Barrett's esophagus who have precancerous cells (dysplasia). The goal is to see if the new meth…
Sponsor: University Hospital, Angers • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Battle of the scopes: which technique best wipes out Barrett's lesions?
Disease control Recruiting nowThis trial compares two endoscopic procedures—endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD)—for removing visible precancerous lesions in people with Barrett's esophagus. About 331 adults with Barrett's esophagus and early-stage abnormal tissue will…
Sponsor: St. Antonius Hospital • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Less is more: thousands skip unnecessary cancer scans in landmark study
Knowledge-focused Recruiting nowThis study follows over 3,000 people with low-risk Barrett's esophagus who have stopped having routine endoscopic surveillance, as recommended by new guidelines. Researchers will track them for at least 10 years to see if stopping these scopes leads to a rise in serious esophagea…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC