Bacterial vaginosis
MONDO:0005316Infection caused by bacterial overgrowth in the vagina. Most affected women are asymptomatic. When symptoms occur, they include foul-smelling vaginal discharge, vaginal itching, and burning. Risk factors include sexual activity with multiple partners and the use of vaginal douches and intrauterine devices. Up to a third of cases resolve without treatment. Antibiotic treatment is recommended when symptoms are present and for women that are pregnant at the time of infection.
Also known as: BV
44 clinical trials for this condition and its sub-types, 44 tagged with Bacterial vaginosis itself.
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Vaginal device aims to boost infection treatment
Disease control Not yet recruitingThis study tests whether a vaginal ovule device, used alongside standard antibiotics or antifungals, improves vaginal health in women with bacterial vaginosis or yeast infections. Eighty women aged 18 to 60 receive either the active device or a placebo ovule over three treatment …
Sponsor: ROELMI HPC • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Blue light could soothe vaginal disorders without hormones
Disease control Not yet recruitingThis study tests whether blue LED light therapy can improve symptoms of common vaginal conditions like menopause-related dryness, bacterial vaginosis, and yeast infections. About 150 women aged 18 to 75 will receive the treatment either at home or in a clinic. Researchers will ch…
Sponsor: Patricia Lordelo • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New vaginal capsule aims to tackle stubborn bacterial vaginosis
Disease control Not yet recruitingThis study tests a new drug called GenSci142, given as a vaginal capsule, for treating bacterial vaginosis (BV). About 30 women with BV will receive either GenSci142 or a standard antibiotic cream to compare safety and how well each works. The goal is to see if the new capsule is…
Phase 1 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Could a 'Vaginal microbiome Transplant' stop recurring BV?
Disease control Not yet recruitingThis phase 2 trial tests whether transferring vaginal fluid from healthy donors can help women aged 18-25 with recurrent bacterial vaginosis (BV). Participants first receive standard antibiotics, then the transplant. The goal is to see if this restores a healthy vaginal microbiom…
Phase 2 • Sponsor: Douglas Kwon • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Can a probiotic stop bacterial vaginosis recurrence?
Disease control Not yet recruitingThis study tests whether a probiotic called Lactobacillus gasseri KABP®064 can prevent bacterial vaginosis (BV) from returning after standard antibiotic treatment. BV is a common vaginal infection that often comes back within a year. The trial will involve 160 women with a histor…
Phase 2/3 • Sponsor: Kaneka Americas Holding Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New hope for preterm labor: simple vaginal tablet may buy extra time for babies
Disease control Not yet recruitingThis study tests whether adding a vaginal tablet containing good bacteria and a low-dose hormone (Gynoflor®) to standard preterm labor treatment can help women stay pregnant longer. About 80 pregnant women between 24 and 33 weeks will receive either the tablet or a placebo for 6 …
Sponsor: Queen Savang Vadhana Memorial Hospital, Thailand • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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New bacterial vaginosis drug passes first safety check in healthy volunteers
Disease control Not yet recruitingThis early-stage trial tests a new drug called GenSci142 in 30 healthy Chinese women to see if it is safe and how the body processes it. Participants receive a single dose of the drug or a placebo, and are monitored for side effects for 15 days. The goal is to gather safety infor…
Phase 1 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can a simple Self-Test cut preterm births in High-Risk pregnancies?
Prevention Not yet recruitingThis trial tests whether a self-administered vaginal swab, analyzed with advanced molecular technology, can detect and treat bacterial imbalances early in pregnancy. Pregnant women at high risk of preterm birth will either receive this screening plus targeted antibiotics or stand…
Phase 3 • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Prevention
Last updated Aug 29, 2026 00:00 UTC
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New combo pill aims to end recurring vaginal infections
Prevention Not yet recruitingThis study tests whether BPR-101 capsules, taken with the antibiotic metronidazole, can prevent bacterial vaginosis (BV) from coming back. Eighty women with BV will receive either the active treatment or a placebo. The main goal is to see if the combination lowers the rate of BV …
Phase 2 • Sponsor: Chengdu Syncor Pharmaceutical Co., Ltd. • Aim: Prevention
Last updated Jun 27, 2026 11:02 UTC
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New vaginal ovule aims to soothe recurrent infections
Symptom relief Not yet recruitingThis study tests a medical device called Rephegyn vaginal ovules to help treat fungal (candidiasis) and bacterial infections. The device is designed to help heal the vaginal lining and reduce symptoms like discharge, pain, and itching. About 34 adults with recurrent infections wi…
Sponsor: Innate srl • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC