Avascular necrosis

Researchers at a Korean hospital are following 210 adults who receive a cementless total hip replacement using the collarless Actis femoral stem. The study focuses on Asian patients, who tend to be younger at surgery and more often need the operation because of lost blood supply …

This study is testing a shoulder replacement device in 300 people with shoulder arthritis, bone death, or rotator cuff tears. Participants receive the implant and are followed for 10 years to see how well it works and if it is safe. The goal is to improve pain and shoulder functi…

This study tests whether alendronate, a drug used for osteoporosis, can help adults with sickle cell disease who have bone damage (osteonecrosis). Thirty participants will take a weekly pill for 24 weeks. The main goals are to see if the treatment is feasible and safe, and to mea…

This study will follow 100 adults who receive the 5C® MEDic Knee System during knee replacement surgery. Researchers want to see how long the implant lasts without needing another operation and track any complications over 5 years. Participants will also fill out health questionn…

This study follows adults who have received a Tipmed shoulder replacement to see how well the implant works and if any problems arise over the first year. Participants have conditions like severe arthritis, rotator cuff damage, or a broken shoulder bone. Researchers track shoulde…

This study follows 50 people who receive a Zimmer Biomet shoulder replacement implant to see if it safely improves pain, movement, and quality of life over two years. Participants have shoulder arthritis, fractures, or other joint damage. The main goal is to measure a meaningful …

This study is testing a new hip replacement system called the HIT Reverse Hip Replacement System. It is for people aged 50 to 75 who need a total hip replacement due to arthritis, joint damage, or other conditions. The goal is to see if the new system is as safe and effective as …

This study follows over 1,000 people who receive a shoulder replacement with FX Shoulder Solutions systems. Researchers will track how often the implant needs to be replaced (revision) and measure pain, movement, and quality of life for up to 10 years after surgery. The goal is t…

This study is following 584 people who received Zimmer Biomet shoulder implants to see how well the devices work over 10 years. Participants have shoulder arthritis, fractures, or deformities. Researchers will track implant survival, pain, function, and any side effects. The goal…

This study follows 368 adults who need a partial hip replacement (hemiarthroplasty) due to fractures, arthritis, or bone death. Researchers will check how well Corin hip devices work and how safe they are over 10 years. The goal is to see if patients can move better and have fewe…

This study compares a robot-assisted system (CORI) to conventional manual instruments for total knee replacement. About 140 participants will be randomly assigned to one of the two methods. The main goal is to see if the robot helps achieve more precise leg alignment after surger…

This study is checking how long the Medacta Shoulder System lasts and how well it works in 200 people with shoulder issues like arthritis, fractures, or failed previous shoulder replacements. Participants will be followed over time to measure shoulder function, pain, and movement…

This study tests whether using a personalized 3D-printed guide during shoulder replacement surgery leads to more accurate placement of the artificial joint. Researchers will compare the precision, bone loss, and surgery time between patients who get the custom guide and those who…

Researchers are testing whether washing the surgical site with antimicrobial solutions after the first cut lowers the amount of Cutibacterium acnes, a bacterium commonly found on the skin, during shoulder replacement surgery. Adults scheduled for a first shoulder replacement are …

Avascular necrosis of the talus happens when the ankle bone loses its blood supply and collapses. Researchers are testing a custom-made implant shaped like the patient's own talus to replace the damaged bone. The study follows 50 adults for five years to see whether the implant r…

This study tests whether a long-acting form of the anesthetic bupivacaine, combined with regular bupivacaine, can control pain better than the standard drug ropivacaine after hip replacement. Sixty adults with hip fractures or necrosis will receive one of the two treatments via a…

This study follows 50 people who have a rare condition where the talus bone in the ankle dies (avascular necrosis). They receive a custom 3D-printed replacement talus, sometimes with a total ankle replacement. Researchers track motion, pain, walking speed, and satisfaction for on…

This study looks at how children and young adults (ages 10 to 25) who had a joint replacement for reasons other than cancer are doing. Researchers will collect information from medical records and questionnaires about quality of life and joint function. The goal is to understand …

This study compares a standard and a new system for collecting bone marrow from the hip. Six adults aged 18–50 having minimally invasive hip repair will provide samples from both hips. The goal is to see which method collects more stem cells, cytokines, and growth factors. No new…

This study follows 2500 people who have had hip replacement surgery with Corin implants. Researchers will check how long the implants last and how well they work over 10, 15, and 20 years. The goal is to gather safety and performance data, not to test a new treatment.