Avascular necrosis
MONDO:0018373Necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure.
Also known as: AVN, avascular necrosis of bone
141 clinical trials for this condition and its sub-types, 80 tagged with Avascular necrosis itself.
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Sub-types of Avascular necrosis
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Primary avascular necrosis 0 trials · 39 incl. sub-types
3 sub-types
- Familial avascular necrosis of femoral head 20 trials · 39 incl. sub-types Sub-types →
- Idiopathic avascular necrosis 1 trial
- Pseudohypoparathyroidism type 1C 0 trials
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Secondary avascular necrosis 1 trial · 38 incl. sub-types
6 sub-types
- Osteonecrosis of the jaw 21 trials
- Gaucher disease type I 12 trials
- Hereditary antithrombin deficiency 3 trials
- Secondary non-traumatic avascular necrosis 1 trial
- Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency 0 trials
- Traumatic avascular necrosis 0 trials
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Dysbaric osteonecrosis 0 trials
Most studied deeper sub-types
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Oxygen chamber therapy put to the test for dozens of diseases
Disease control Not yet recruitingThis study will test hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — for over 30 conditions, including long COVID, Crohn's disease, frostbite, and multiple sclerosis. Researchers will track 100 patients to see if HBOT improves their quality of …
Phase 4 • Sponsor: Jay C. Buckey Jr. • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Oxygen therapy may boost hip procedure for bone death
Disease control Not yet recruitingThis study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to a standard hip procedure (core decompression with bone marrow cells) can reduce pain in people with early-stage avascular necrosis of the hip. The trial will enroll 400 p…
Sponsor: Yale University • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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CT scans track hip implant movement to predict Long-Term stability
Knowledge-focused Not yet recruitingThis study tracks 30 people receiving a CATALYSTEM cementless hip implant to measure how much the stem moves (subsides) in the thigh bone over two years. Using specialized CT scans, researchers aim to see if the implant stays firmly in place, which is key for long-term success. P…
Sponsor: Canadian Radiostereometric Analysis Network • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC