Autoimmune polyendocrine syndrome type 1
MONDO:0009411Autoimmune polyendocrinopathy type 1, or APECED syndrome, is a genetic disease that manifests in childhood or early adolescence with a combination of chronic mucocutaneous candidiasis, hypoparathyroidism and autoimmune adrenal failure.
Also known as: AIRE autoimmune polyendocrinopathy, APECED syndrome, APS type 1, APS1, Autoimmune Polyglandular Syndrome Type 1, MEDAC syndrome, Whitaker syndrom, aire autoimmune polyendocrinopathy
48 clinical trials for this condition and its sub-types, 8 tagged with Autoimmune polyendocrine syndrome type 1 itself.
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Pump delivery of hormone may steady calcium levels in rare disorder
Disease control CompletedThis study tested two ways of delivering synthetic parathyroid hormone (PTH) to people with chronic hypoparathyroidism, a condition where the body doesn't make enough PTH, causing low calcium. Researchers compared using an insulin pump to give steady, small doses versus twice-dai…
Phase 2 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New study aims to crack the code of autoimmune diseases
Knowledge-focused CompletedThis study is collecting blood, urine, and stool samples from 500 children with autoimmune diseases and healthy controls. Researchers will analyze these samples to find molecular patterns that could help diagnose these conditions and guide treatment decisions. The goal is to crea…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Rare disease genetics unlocked: new study maps APECED mutations
Knowledge-focused CompletedThis study looked at the genetic makeup of 29 people with APECED syndrome, a rare autoimmune disorder. Researchers aimed to find common gene mutations and link them to symptoms. The goal was to better understand the disease and improve diagnosis.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC