Atopic keratoconjunctivitis

MONDO:0015599

Atopic keratoconjunctivitis is a rare and chronic allergic disease of the cornea and conjunctiva occurring in all age groups characterized by severe itching and burning sensation, conjunctival injection, photophobia and edema with serious cases leading to ulceration of the cornea which can result in blindness. It is often associated with atopic dermatitis.

1 clinical trial for this condition and its sub-types, 1 tagged with Atopic keratoconjunctivitis itself.

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Where it sits in the disease tree

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↑ Eye disorder (3079)

Including sub-types (1) Tagged with Atopic keratoconjunctivitis (1)

Trials to join now! 1

New eye drops aim to stop itching and eye damage from severe allergies

Symptom relief Recruiting now

This Phase 3 trial tests DFL24498 eye drops in 138 adults with atopic keratoconjunctivitis (AKC), a severe allergic eye condition. The drops are given twice daily for 12 weeks to see if they reduce eye itching and corneal damage compared to a placebo. Participants must have AKC i…

Phase 3 • Sponsor: Dompé Farmaceutici S.p.A • Aim: Symptom relief

Last updated Sep 21, 2026 15:00 UTC

Atopic keratoconjunctivitis

Where it sits in the disease tree

New eye drops aim to stop itching and eye damage from severe allergies