Arteriovenous malformations of the brain
MONDO:0007154Cerebral arteriovenous malformation (AVM) is a congenital malformative communication between the veins and the arteries in the brain in the form of a nidus, an anatomical structure composed of dilated and tangled supplying arterioles and drainage veins with no intervening capillary bed, that can be asymptomatic or cause, depending on the location and the size of the AVM, headaches of varying severity, generalized or focal seizures, focalneurological defects (weakness, numbness, speech difficulties, vision loss) or potentially fatal intracranial hemorrhage in case the AVM ruptures.
Also known as: arteriovenous malformation of the brain, somatic, arteriovenous malformations of the brain, cerebral arteriovenous malformation, intracranial arteriovenous malformation, intracranial haemorrhage in brain cerebrovascular malformations, susceptibility to, somatic mutation, intracranial hemorrhage in brain cerebrovascular malformations, susceptibility to, somatic mutation, Bavm, cerebral arteriovenous malformations
1469 clinical trials for this condition and its sub-types, 32 tagged with Arteriovenous malformations of the brain itself.
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New wire aims to make brain surgery safer
Disease control CompletedThis study tested a new medical wire, called the Tarvos Microguidewire, used during surgery on blood vessels in the brain. The wire helps doctors guide other tools to the right spot. Researchers looked back at records of 121 patients who had this wire used in their surgery for co…
Sponsor: Keuro MedTech • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New combo for blocking blood vessels shows safety in rare vascular conditions
Disease control CompletedThis study looked at the safety of using Lipiodol® Ultra Fluid (a contrast dye) together with surgical glues to block abnormal blood vessels in 132 adults with conditions like hemangiomas or arteriovenous malformations. The procedure was done as part of their regular treatment pl…
Phase 4 • Sponsor: Guerbet • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Cancer drug shows promise for rare blood vessel disorder in tiny trial
Disease control CompletedThis small, completed study tested the cancer drug cobimetinib (Cotellic) in just 3 people with extracranial arteriovenous malformations (AVMs), which are abnormal tangles of blood vessels. The goal was to see if the drug could shrink the AVM by at least 20% and to check for safe…
Phase 2 • Sponsor: University of Arkansas • Aim: Disease control
Last updated Jun 26, 2026 16:11 UTC
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Eye test may spot brain trouble
Knowledge-focused CompletedThis small pilot study tested whether a non-invasive eye scan called OCTA can detect changes in the brain related to stroke and other neurological conditions. Researchers compared eye scans from 7 people with brain diseases and healthy volunteers. The goal was to gather early dat…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Large study aims to predict brain bleeds in rare HHT disorder
Knowledge-focused CompletedThis study looked at over 2,200 people with hereditary hemorrhagic telangiectasia (HHT), a rare condition that causes abnormal blood vessels. The goal was to find out what makes some people with HHT more likely to have a brain bleed. Researchers collected health information, bloo…
Sponsor: Unity Health Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Real-World data on HydroPearl embolization through the wrist
Knowledge-focused CompletedThis completed registry study collected real-world data on 99 patients receiving HydroPearl microspheres to block blood flow to conditions like uterine fibroids, arteriovenous malformations, hypervascular tumors, and benign prostatic hyperplasia. The procedure was done through th…
Sponsor: Terumo Medical Corporation • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:23 UTC