Aplastic anemia
MONDO:0015909Anemia resulting from bone marrow failure (aplastic or hypoplastic bone marrow). The production of erythroblasts and red cells is markedly decreased, and it may be associated with decreased production of granulocytes (granulocytopenia) and platelets (thrombocytopenia) as well. Aplastic anemia may be idiopathic or secondary due to bone marrow damage by toxins, radiation, or immunologic factors.
418 clinical trials for this condition and its sub-types, 110 tagged with Aplastic anemia itself.
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Sub-types of Aplastic anemia
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Acquired aplastic anemia 38 trials · 303 incl. sub-types
3 sub-types
- Primary myelofibrosis 191 trials · 195 incl. sub-types Sub-types →
- Paroxysmal nocturnal hemoglobinuria 73 trials Sub-types →
- Primary acquired red cell aplasia 0 trials · 2 incl. sub-types Sub-types →
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Inherited aplastic anemia 2 trials · 53 incl. sub-types
5 sub-types
- Fanconi anemia 29 trials · 42 incl. sub-types Sub-types →
- Diamond-Blackfan anemia 17 trials Sub-types →
- WT limb-blood syndrome 0 trials
- Autosomal dominant aplasia and myelodysplasia 0 trials
- Pancytopenia-developmental delay syndrome 0 trials
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Idiopathic aplastic anemia 9 trials
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Myelophthisic anemia 0 trials
Most studied deeper sub-types
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Experimental drug for rare bone marrow disease shows early promise, but study halted
Disease control Stopped earlyThis study tested an experimental drug called REGN7257 in 17 people with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. The drug was given to patients whose disease did not get better or came back after standard immune-suppressing …
Phase 1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New combo therapy for rare blood disorder shows promise
Disease control Stopped earlyThis study looked at whether adding a drug called G-CSF to the usual treatment (ATG and Cyclosporin A) helps people with newly diagnosed severe aplastic anemia. Severe aplastic anemia is a rare condition where the bone marrow stops making enough blood cells. The trial included 20…
Phase 3 • Sponsor: European Society for Blood and Marrow Transplantation • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Experimental anemia drug trial halted after only 3 patients
Disease control Stopped earlyThis study tested a low-dose chemotherapy drug (decitabine) in people with a severe type of anemia that did not improve with standard treatments. Only 3 people were enrolled before the study was stopped early. The goal was to see if the drug could improve blood cell counts and re…
Phase 2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC