Aortic valve disease 2
MONDO:0013902Any aortic valve disease in which the cause of the disease is a mutation in the SMAD6 gene.
Also known as: SMAD6 aortic valve disease, aortic valve disease 2, aortic valve disease caused by mutation in SMAD6, aortic valve disease type 2, AOVD2, aortic valve stenosis, bicuspid aortic valve
67 clinical trials for this condition and its sub-types, 12 tagged with Aortic valve disease 2 itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
New heart valve trial aims to improve Second-Time valve replacements
Disease control Not yet recruitingThis trial is for people whose surgically implanted aortic heart valve has stopped working properly. It compares two types of replacement valves placed through a tube in the leg (TAVI): a newer self-expanding valve (Hydra) versus standard balloon-expandable valves (Sapien or MyVa…
Sponsor: National University of Ireland, Galway, Ireland • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
-
New bendable tube could make heart valve surgery safer
Disease control Not yet recruitingThis trial tests a new device called the ArcFlex Sheath, a bendable tube used during TAVR surgery to replace a faulty aortic valve. The goal is to see if it helps doctors position the new valve more easily and safely compared to a standard sheath. About 180 people who need TAVR s…
Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC