Antisynthetase syndrome
MONDO:0019344Antisynthetase (AS) syndrome is a clinically heterogeneous form of idiopathic inflammatory myopathy characterized by myositis, arthralgia, Raynaud phenomenon, mechanic hands, interstitial lung disease (ILD), and serum autoantibodies to aminoacyl transfer RNA synthetases (anti-ARS).
Also known as: AS syndrome, anti-Jo1 syndrome
28 clinical trials for this condition and its sub-types, 21 tagged with Antisynthetase syndrome itself.
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Can a new pill ease muscle weakness in myositis?
Disease control Not yet recruitingThis phase III trial tests whether the oral drug nerandomilast can improve symptoms of idiopathic inflammatory myopathies, a group of rare autoimmune diseases that cause muscle weakness and inflammation. Adults with active myositis are randomly assigned to take nerandomilast or a…
Phase 3 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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New study aims to predict best treatments for rheumatoid diseases using AI and health data
Knowledge-focused Not yet recruitingThis study will collect health information, samples, and data from 100 people in Luxembourg (800 total across Europe) who have rheumatoid diseases and are starting or changing treatment. Researchers hope to find patterns that can predict which treatments work best for each person…
Sponsor: Luxembourg Institute of Health • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:31 UTC