Anemia due to chronic disorder

This phase 2 trial tests a drug called DISC-0974 in 21 adults with inflammatory bowel disease (IBD) who also have anemia caused by inflammation. The study aims to see if the drug safely raises hemoglobin levels compared to a placebo. Participants receive injections of either DISC…

This study tests whether enarodustat, an oral medication, can effectively raise hemoglobin levels in adults with anemia from chronic kidney disease (CKD) who are not on dialysis. Participants will take enarodustat daily, with doses adjusted to reach a target hemoglobin range, and…

This phase 3 trial tests roxadustat, an oral medication, for treating anemia in children and teenagers with chronic kidney disease. About 100 participants will take the drug three times a week for up to a year. The goal is to see if it can safely raise hemoglobin levels and offer…

This study tests a new drug called efepoetin alfa for treating anemia in adults with advanced chronic kidney disease who are on dialysis. About 429 participants will receive either the new drug or an existing one to compare safety and effectiveness. The main goal is to see if the…

This Phase 3 trial tests an oral drug called AND017 for anemia in people on dialysis due to end-stage kidney disease. About 300 participants will receive either AND017 capsules or a standard injected ESA. The goal is to see if AND017 can maintain healthy hemoglobin levels as well…

This Phase 3 trial tests an oral drug called AND017 against standard injected ESA therapy for anemia in people with chronic kidney disease who are not on dialysis. About 240 participants will receive either AND017 or ESA to see which better maintains healthy hemoglobin levels ove…

This study tests a new long-acting drug called pegmolesatide for anemia in people with chronic kidney disease who are on dialysis. It aims to see if switching from current anemia treatments to this drug is safe and effective. About 96 adults will receive the drug for 12 weeks and…

This study tests a new drug called pegmolesatide, alone or combined with roxadustat, to treat anemia in 240 adults on dialysis for chronic kidney disease. Participants currently on another anemia drug (rHuEPO) will switch to one of three treatment plans for 24 weeks. The goal is …

This study is observing 1000 adults having moderate- to high-risk surgery to see if the type and severity of anemia they have before surgery affects their risk of complications like heart injury, kidney injury, or stroke. Researchers will compare patients with iron-deficiency ane…