Anaplastic/large cell medulloblastoma
MONDO:0016709A medulloblastoma composed of sheets of large cells mixed with cells characterized by marked nuclear pleomorphism and high mitotic activity.
Also known as: large cell/anaplastic medulloblastoma
1508 clinical trials for this condition and its sub-types, 2 tagged with Anaplastic/large cell medulloblastoma itself.
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New combination therapy aims to outsmart aggressive childhood brain cancer
Disease control CompletedThis phase 3 trial investigates whether adding carboplatin and isotretinoin to standard radiation and chemotherapy improves outcomes for children and young adults with high-risk medulloblastoma, a fast-growing brain tumor. Participants receive radiation therapy along with several…
Phase 3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New hope for toddlers with brain cancer: stem cell rescue trial
Disease control CompletedThis study looked at 91 children under 3 years old with aggressive brain tumors. It compared two intense chemotherapy plans, one with and one without methotrexate, followed by a stem cell transplant. The goal was to see which approach led to more complete tumor disappearance.
Phase 3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC