Anal melanoma

MONDO:0006081

A melanoma arising from the anus. Clinical presentation includes rectal bleeding, tenesmus, pain, and change in bowel habit. The prognosis is usually poor.

Also known as: anal malignant melanoma, anal melanoma, anus melanoma, anus melanoma (disease), malignant anus melanoma, malignant melanoma of anus, malignant melanoma of the anus, melanoma (disease) of anus

2875 clinical trials for this condition and its sub-types, 2 tagged with Anal melanoma itself.

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Where it sits in the disease tree

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Part of

↑ Anus cancer (133) ↑ Rectum malignant melanoma (2)

Including sub-types (2875) Tagged with Anal melanoma (2)

Trials to join now! 1 Not yet finished but already full! 1

New combo therapy aims to shrink rare melanomas before surgery

Disease control Recruiting now

This study is testing whether giving radiation therapy along with immunotherapy before surgery can improve outcomes for people with sinonasal or anorectal mucosal melanoma, two rare and aggressive cancers. About 40 participants will receive combination immunotherapy (such as ipil…

Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Sep 12, 2026 00:00 UTC

Anal melanoma

Where it sits in the disease tree

New combo therapy aims to shrink rare melanomas before surgery