Alport syndrome
MONDO:0018965A rare renal disease characterized by glomerular nephropathy with hematuria progressing to end-stage renal disease (ESRD), frequently associated with sensorineural deafness, and occasionally with ocular anomalies.
Also known as: hereditary nephritis, Alport deafness-nephropathy, Alport syndrome, Alport's syndrome
20 clinical trials for this condition and its sub-types, 17 tagged with Alport syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Alport syndrome
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X-linked Alport syndrome 3 trials
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Autosomal recessive Alport syndrome 2 trials
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Autosomal dominant Alport syndrome 0 trials
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Digenic Alport syndrome 0 trials
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New drug aims to slow kidney failure in rare genetic disease
Disease control OngoingThis study tests an experimental drug called BAY 3401016 in 60 adults aged 18 to 45 with Alport syndrome, a rare genetic condition that damages kidneys, hearing, and eyes. The drug works by blocking a protein thought to cause kidney injury, with the goal of slowing the loss of ki…
Phase 2 • Sponsor: Bayer • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New drug aims to plug kidney leaks in multiple diseases
Disease control OngoingThis phase 2 study tests the drug atrasentan in 103 adults with various kidney diseases that cause protein leakage, including IgA nephropathy and FSGS. Participants take a daily tablet to see if it reduces protein in urine, a sign of kidney damage. The goal is to find a new way t…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC