ALK-positive anaplastic large cell lymphoma
MONDO:0017602ALK-positive anaplastic large cell lymphoma (ALK+ ALCL) is a type of ALCL, a rare and aggressive peripheral T-cell non-Hodgkin lymphoma affecting lymph nodes and extranodal sites, which is characterized by the expression of a protein called anaplastic lymphoma kinase (ALK).
Also known as: ALCL, ALK+, ALK+ ALCL, ALK+ anaplastic large cell lymphoma, ALK-positive anaplastic large cell lymphoma, ALKoma, anaplastic large cell lymphoma, ALK-positive
1961 clinical trials for this condition and its sub-types, 22 tagged with ALK-positive anaplastic large cell lymphoma itself.
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Engineered donor cells take on lymphoma in early trial
Disease control OngoingThis early-phase study tests a new approach for patients with certain lymphomas (Hodgkin, NK/T-cell, and others) that have returned or not responded to treatment. The therapy uses immune cells from healthy donors that are specially trained in the lab to attack cancer cells carryi…
Phase 1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New combo shows promise against tough lymphoma
Disease control OngoingThis phase 2 trial tests a new combination treatment for a rare type of lymphoma (CD30-positive peripheral T-cell lymphoma). It combines a targeted drug (brentuximab vedotin) with standard chemotherapy. The goal is to see if this approach improves the number of patients who achie…
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Cancer-Fighting virus teams up with immunotherapy to tackle rare skin tumors
Disease control OngoingThis phase II trial is testing whether a combination of talimogene laherparepvec (a modified herpes virus that infects and kills cancer cells) and nivolumab (an immunotherapy drug) can shrink tumors in people with rare skin cancers or lymphomas that haven't responded to standard …
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Promising combo tackles rare blood cancer in chinese patients
Disease control OngoingThis study tests a combination of brentuximab vedotin plus standard chemotherapy (CHP) in 52 Chinese adults with a rare type of lymphoma called CD30+ peripheral T-cell lymphoma. The goal is to see how well the treatment shrinks tumors and to monitor side effects. Participants rec…
Phase 2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New hope for blood cancer patients in japan?
Disease control OngoingThis study is testing a new drug called Golcadomide (BMS-986369) in about 85 people in Japan whose T-cell lymphoma has come back or not responded to treatment. The goal is to check the drug's safety and how well it works against the cancer. Participants will receive the drug and …
Phase 1/2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Immunotherapy drug nivolumab takes on rare blood cancer in kids and adults
Disease control OngoingThis study tests the immunotherapy drug nivolumab in 45 children and adults with a rare blood cancer called ALK-positive anaplastic large cell lymphoma that has come back or not responded to treatment. Participants are split into two groups: those with active disease to see if th…
Phase 2 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC