Aldosterone-producing adrenal cortex adenoma
MONDO:0016505An adenoma of the adrenal cortex that produces aldosterone. It may be associated with Conn syndrome. Clinical presentation includes hypertension, hypokalemia, and muscle weakness.
Also known as: APAC, Pure APAC, Pure aldosterone-producing adrenocortical carcinoma, Pure aldosterone-secreting adrenocortical carcinoma, aldosterone producing adrenal cortex adenoma, aldosterone producing adrenal cortical adenoma, aldosterone-producing adrenal cortex adenoma, adrenocortical carcinoma with pure aldosterone hypersecretion
1450 clinical trials for this condition and its sub-types, 8 tagged with Aldosterone-producing adrenal cortex adenoma itself.
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Zapping adrenal tumors could lower blood pressure without surgery
Disease control CompletedThis study tested a procedure called radiofrequency ablation, which uses heat to destroy a small adrenal gland tumor that causes high blood pressure. Researchers wanted to see if it could safely lower blood pressure in 31 patients with primary aldosteronism. The goal was to reduc…
Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can a new PET scan light up hidden adrenal tumors causing high blood pressure?
Diagnosis CompletedThis trial is testing whether a new radioactive tracer, [18F]AlF-NOTA-pentixather, can accurately identify aldosterone-producing adenomas (benign adrenal tumors) in people with primary aldosteronism—a condition where the adrenal glands make too much aldosterone, leading to high b…
Sponsor: Sichuan Provincial People's Hospital • Aim: Diagnosis
Last updated Aug 20, 2026 00:00 UTC
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New screening strategy could speed diagnosis of inherited aldosteronism
Diagnosis CompletedThis study tests a new screening method to tell apart two causes of high blood pressure: a rare genetic condition called Glucocorticoid-Remediable Aldosteronism (GRA) and a more common adrenal tumor. The approach combines an overnight dexamethasone suppression test with detailed …
Sponsor: Peking Union Medical College Hospital • Aim: Diagnosis
Last updated Jul 16, 2026 00:00 UTC