Aggressive B-cell non-Hodgkin lymphoma
MONDO:0017595Also known as: aggressive B-cell NHL
3014 clinical trials for this condition and its sub-types, 69 tagged with Aggressive B-cell non-Hodgkin lymphoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Aggressive B-cell non-Hodgkin lymphoma
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Diffuse large B-cell lymphoma 633 trials · 755 incl. sub-types
30 sub-types
- Relapsed/refractory diffuse large B-cell lymphoma 210 trials
- High grade B-cell lymphoma 185 trials
- Primary mediastinal large B-cell lymphoma 175 trials
- T-cell/histiocyte rich large B cell lymphoma 31 trials
- Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly 23 trials
- Diffuse large B-cell lymphoma of the central nervous system 21 trials
- Plasmablastic lymphoma 20 trials
- Primary effusion lymphoma 18 trials
- Diffuse large B-cell lymphoma germinal center B-cell type 13 trials
- Diffuse large B-cell lymphoma activated B-cell type 9 trials
- Lymphomatoid granulomatosis 3 trials · 7 incl. sub-types Sub-types →
- Primary cutaneous diffuse large B-cell lymphoma, Leg type 7 trials
- ALK-positive large B-cell lymphoma 5 trials
- Intravascular large B-cell lymphoma 4 trials
- Diffuse large B-cell lymphoma with chronic inflammation 3 trials
- Primary vitreoretinal large b-cell lymphoma 3 trials
- EZB diffuse large B-cell lymphoma 0 trials · 2 incl. sub-types Sub-types →
- MCD diffuse large B-cell lymphoma 1 trial
- Breast diffuse large B-cell lymphoma 1 trial
- A53 diffuse large B-cell lymphoma 0 trials
- BN2 diffuse large B-cell lymphoma 0 trials
- N1 diffuse large B-cell lymphoma 0 trials
- ST2 diffuse large B-cell lymphoma 0 trials
- Colorectal diffuse large B-cell lymphoma 0 trials
- Gastric diffuse large B-cell lymphoma 0 trials
- Liver diffuse large B-cell lymphoma 0 trials
- Primary pulmonary diffuse large B-cell lymphoma 0 trials
- Small intestinal diffuse large B-cell lymphoma 0 trials
- Splenic diffuse large B-cell lymphoma 0 trials
- Thyroid gland diffuse large B-cell lymphoma 0 trials
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Mantle cell lymphoma 331 trials
2 sub-types
- Gastric mantle cell lymphoma 0 trials
- Splenic mantle cell lymphoma 0 trials
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Burkitt lymphoma 221 trials
2 sub-types
- Colon Burkitt lymphoma 0 trials
- Small intestinal Burkitt lymphoma 0 trials
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Precursor B-cell acute lymphoblastic leukemia 68 trials · 113 incl. sub-types
2 sub-types
- B-cell childhood acute lymphoblastic leukemia 37 trials
- B-cell adult acute lymphocytic leukemia 12 trials
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B-cell prolymphocytic leukemia 7 trials
Most studied deeper sub-types
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Can a smart immune cell with a kill switch beat tough lymphomas?
Cure Not yet recruitingThis Phase 1 trial tests a new type of cell therapy for people with relapsed or refractory CD30-positive lymphomas, including Hodgkin lymphoma and certain non-Hodgkin lymphomas. The treatment uses a patient's own immune cells that are genetically engineered to recognize and attac…
Phase 1 • Sponsor: The Methodist Hospital Research Institute • Aim: Cure
Last updated Jul 29, 2026 00:00 UTC
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New cell therapy targets Hard-to-Treat lymphoma
Disease control Not yet recruitingThis study tests a new treatment called SYS6055 for people with aggressive B-cell lymphoma that has come back or not responded to standard therapy. The treatment uses specially designed cells to target and attack cancer cells. The trial will check if it is safe, what dose works b…
Phase 1/2 • Sponsor: Beijing Kangchuanglian Biopharmaceutical Technology Research Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Can a vitamin D2 blast speed up recovery in lymphoma patients?
Disease control Not yet recruitingThis study compares a high-intensity loading dose of vitamin D2 to standard weekly dosing in 52 patients with newly diagnosed aggressive non-Hodgkin lymphoma who are also receiving standard chemotherapy. The goal is to see if the high-dose approach normalizes vitamin D levels fas…
Sponsor: Phramongkutklao College of Medicine and Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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New hope for Hard-to-Treat lymphoma: drug cocktail shows promise
Disease control Not yet recruitingThis phase 2 trial tests a combination of three drugs (glofitamab, polatuzumab vedotin, and chemotherapy) in 80 adults with aggressive B-cell lymphoma that has come back or not responded to treatment. The goal is to see if this cocktail can shrink tumors and improve survival. The…
Phase 2 • Sponsor: Navy General Hospital, Beijing • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Immune 'hotness' and growth markers may sharpen lymphoma prognosis
Knowledge-focused Not yet recruitingThis study examines tissue samples from 70 people with diffuse large B-cell lymphoma and other aggressive B-cell lymphomas. Researchers will measure immune cell infiltration, called tumor 'hotness', and the Ki-67 proliferation index using two scoring methods. The goal is to see i…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Can blood tests and scans track lymphoma in real time? new study aims to find out.
Knowledge-focused Not yet recruitingThis study will test whether doctors can quickly and accurately monitor minimal residual disease (tiny amounts of cancer left after treatment) in people with aggressive B-cell lymphoma. Researchers will use blood tests to look for tumor DNA and PET scans to see if results can be …
Sponsor: The Lymphoma Academic Research Organisation • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC